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C Flament

Explore the profile of C Flament including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 2358
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Recent Articles
1.
Messaoudene M, Mourikis T, Michels J, Fu Y, Bonvalet M, Lacroix-Trikki M, et al.
Ann Oncol . 2019 Mar; 30(6):934-944. PMID: 30924846
Background: Tumor-infiltrating lymphocytes (TILs) represent a prognostic factor for survival in primary breast cancer (BC). Nonetheless, neoepitope load and TILs cytolytic activity are modest in BC, compromising the efficacy of...
2.
Jacquelot N, Roberti M, Enot D, Rusakiewicz S, Ternes N, Jegou S, et al.
Nat Commun . 2017 Sep; 8(1):592. PMID: 28928380
Immune checkpoint blockers (ICB) have become pivotal therapies in the clinical armamentarium against metastatic melanoma (MMel). Given the frequency of immune related adverse events and increasing use of ICB, predictors...
3.
Wemeau M, Kepp O, Tesniere A, Panaretakis T, Flament C, De Botton S, et al.
Cell Death Dis . 2011 Mar; 1:e104. PMID: 21368877
Experiments performed in mice revealed that anthracyclines stimulate immunogenic cell death that is characterized by the pre-apoptotic exposure of calreticulin (CRT) on the surface of dying tumor cells. Here, we...
4.
Andre F, Schartz N, Chaput N, Flament C, Raposo G, Amigorena S, et al.
Vaccine . 2002 Dec; 20 Suppl 4:A28-31. PMID: 12477425
Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells induce immune-mediated anti-tumor response in mice. Here,...
5.
Andre F, Andersen M, Wolfers J, Lozier A, Raposo G, Serra V, et al.
Adv Exp Med Biol . 2002 Jan; 495:349-54. PMID: 11774591
No abstract available.
6.
Graner F, Jiang Y, Janiaud E, Flament C
Phys Rev E Stat Nonlin Soft Matter Phys . 2001 Apr; 63(1 Pt 1):011402. PMID: 11304255
We study the equilibrium energies of two-dimensional (2D) noncoarsening fluid foams, which consist of bubbles with fixed areas. The equilibrium states correspond to local minima of the total perimeter. We...
7.
Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C, et al.
Nat Med . 2001 Mar; 7(3):297-303. PMID: 11231627
The initiation of T-cell-mediated antitumor immune responses requires the uptake and processing of tumor antigens by dendritic cells and their presentation on MHC-I molecules. Here we show in a human...
8.
Merad M, Angevin E, Wolfers J, Flament C, Lorenzi I, Triebel F, et al.
J Immunother . 2000 Jun; 23(3):369-78. PMID: 10838666
The combination of interferon-alpha (IFN-alpha) plus interleukin (IL-2) has been accepted in the treatment of metastatic renal cell carcinoma (MRCC), whereas vaccines based on IL-12 or dendritic cells (DCs) are...
9.
Fernandez N, Lozier A, Flament C, Ricciardi-Castagnoli P, Bellet D, Suter M, et al.
Nat Med . 1999 Apr; 5(4):405-11. PMID: 10202929
Cytotoxic T lymphocytes and natural killer cells are essential effectors of anti-tumor immune responses in vivo. Dendritic cells (DC) 'prime' tumor antigen-specific cytotoxic T lymphocytes; thus, we investigated whether DC...
10.
Zitvogel L, Regnault A, Lozier A, Wolfers J, Flament C, Tenza D, et al.
Nat Med . 1998 May; 4(5):594-600. PMID: 9585234
Dendritic cells (DCs) are professional antigen presenting cells with the unique capacity to induce primary and secondary immune responses in vivo. Here, we show that DCs secrete antigen presenting vesicles,...