C Chris Yun
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Explore the profile of C Chris Yun including associated specialties, affiliations and a list of published articles.
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Articles
67
Citations
1565
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Recent Articles
1.
Yun C
Am J Physiol Gastrointest Liver Physiol
. 2024 Nov;
328(1):G49-G50.
PMID: 39589437
No abstract available.
2.
Yun C, Han Y, McConnell B
Cell Mol Gastroenterol Hepatol
. 2024 Sep;
18(6):101398.
PMID: 39233124
The intestinal epithelium undergoes continuous homeostatic renewal to conduct the digestion and absorption of nutrients. At the same time, the intestinal epithelial barrier separates the host from the intestinal lumen,...
3.
McConnell B, Liang Z, Xu C, Han Y, Yun C
Am J Physiol Gastrointest Liver Physiol
. 2024 Apr;
326(6):G631-G642.
PMID: 38593468
Lysophosphatidic acid (LPA) is a bioactive lipid molecule that regulates a wide array of cellular functions, including proliferation, differentiation, and survival, via activation of cognate receptors. The LPA receptor is...
4.
Han Y, Bagchi P, Yun C
Am J Physiol Cell Physiol
. 2023 Dec;
326(1):C50-C59.
PMID: 38047302
Electroneutral NaCl transport by Na/H exchanger 3 (NHE3, ) is the major Na absorptive mechanism in the intestine and decreased NHE3 activity contributes to diarrhea. Patients with diabetes often experience...
5.
Han Y, Srinivasan S, Yun C
Am J Physiol Endocrinol Metab
. 2023 Jul;
325(3):E214-E226.
PMID: 37467022
Gastrointestinal (GI) complications, including diarrhea, constipation, and gastroparesis, are common in patients with diabetes. Dysregulation of the Na/H exchanger NHE3 in the intestine is linked to diarrhea and constipation, and...
6.
Liang Z, Yun C
Cells
. 2022 Jul;
11(14).
PMID: 35883686
Renewal of the intestinal epithelium is orchestrated by regenerative epithelial proliferation within crypts. Recent studies have shown that lysophosphatidic acid (LPA) can maintain intestinal epithelial renewal in vitro and conditional...
7.
Han Y, Yun C
Front Physiol
. 2022 Apr;
13:867244.
PMID: 35444557
Glycemic control is the key to the management of type 2 diabetes. Metformin is an effective, widely used drug for controlling plasma glucose levels in diabetes, but it is often...
8.
Liang Z, He P, Han Y, Yun C
Cell Mol Gastroenterol Hepatol
. 2022 Apr;
14(1):129-150.
PMID: 35390517
Background & Aims: Regeneration of the epithelium by stem cells in the intestine is supported by intrinsic and extrinsic factors. Lysophosphatidic acid (LPA), a bioactive lipid mediator, regulates many cellular...
9.
Jenkin K, Han Y, Lin S, He P, Yun C
Cell Mol Gastroenterol Hepatol
. 2021 Nov;
13(3):695-716.
PMID: 34823064
Background & Aims: Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na/H exchanger NHE3 (hNHE3), but not...
10.
Wang M, He P, Han Y, Dong L, Yun C
Cell Mol Gastroenterol Hepatol
. 2021 May;
12(3):1073-1092.
PMID: 33975030
Background & Aims: Epithelial cells form a monolayer at mucosal surface that functions as a highly selective barrier. Lysophosphatidic acid (LPA) is a bioactive lipid that elicits a broad range...