C A Dionne
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Explore the profile of C A Dionne including associated specialties, affiliations and a list of published articles.
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44
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1408
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Recent Articles
11.
Flood D, Finn J, Walton K, Dionne C, Contreras P, Miller M, et al.
J Comp Neurol
. 1998 Aug;
398(3):373-92.
PMID: 9714150
Cell survival, death, and stress signals are transduced from the cell surface to the cytoplasm and nucleus via a cascade of phosphorylation events involving the mitogen-activated protein kinase (MAPK) family....
12.
Glicksman M, Chiu A, Dionne C, Harty M, Kaneko M, Murakata C, et al.
J Neurobiol
. 1998 Jun;
35(4):361-70.
PMID: 9624618
CEP-1347, also known as KT7515, a derivative of a natural product indolocarbazole, inhibited motor neuronal death in vitro, inhibited activation of the stress-activated kinase JNK1 (c-jun NH terminal kinase) in...
13.
Bhat R, Engber T, Finn J, Koury E, Contreras P, Miller M, et al.
J Neurochem
. 1998 Feb;
70(2):558-71.
PMID: 9453550
In vitro studies indicate that p42/p44MAPK phosphorylate both nuclear and cytoplasmic proteins. However, the functional targets of p42/p44MAPK activation in vivo remain unclear. To address this question, we localized activated...
14.
Angeles T, Yang S, Steffler C, Dionne C
Arch Biochem Biophys
. 1998 Feb;
349(2):267-74.
PMID: 9448714
The kinetic mechanism of the trk receptor-linked tyrosine kinase was determined using a baculovirus expressed trk kinase domain and a bacterially expressed phospholipase C-gamma/glutathione S-transferase (PLC-gamma/ GST) fusion protein as...
15.
Maroney A, Glicksman M, Basma A, Walton K, KNIGHT Jr E, Murphy C, et al.
J Neurosci
. 1998 Jan;
18(1):104-11.
PMID: 9412490
Neurons undergoing apoptosis can be rescued by trophic factors that simultaneously increase the activity of extracellular signal-regulated kinase (ERK) and decrease c-Jun N-terminal kinase (JNK) and p38. We identified a...
16.
Camoratto A, Jani J, Angeles T, Maroney A, Sanders C, Murakata C, et al.
Int J Cancer
. 1997 Aug;
72(4):673-9.
PMID: 9259409
The present report describes the in vitro and in vivo profile of CEP-751, a novel receptor tyrosine kinase inhibitor. CEP-751 at 100 nM inhibits the receptor tyrosine kinase activity of...
17.
Kaneko M, Saito Y, Saito H, Matsumoto T, Matsuda Y, Vaught J, et al.
J Med Chem
. 1997 Jun;
40(12):1863-9.
PMID: 9191963
A series of 3,9 disubstituted [(alkylthio)methyl]- and (alkoxymethyl)-K-252a derivatives was synthesized with the aim of enhancing and separating the neurotrophic properties from the undesirable NGF (trk A kinase) and PKC...
18.
KNIGHT Jr E, Connors T, Maroney A, Angeles T, Hudkins R, Dionne C
Anal Biochem
. 1997 May;
247(2):376-81.
PMID: 9177701
The high-affinity receptor for nerve growth factor (NGF), trkA, is a receptor-linked tyrosine kinase. The binding of NGF to trkA, depending on the context of its environment, can cause beneficial...
19.
Han J, Dionne C, Kedersha N, Goldmacher V
Cancer Res
. 1997 Jan;
57(1):176-82.
PMID: 8988061
To better understand the effects of p53 on the process of DNA damage-induced cell death, we examined the influence of p53 status on the rate of the onset and the...
20.
Maroney A, Sanders C, Neff N, Dionne C
J Neurochem
. 1997 Jan;
68(1):88-94.
PMID: 8978713
K-252b potentiates the neurotrophic effects of neurotrophin-3 (NT-3) in primary cultures of rat central cholinergic and peripheral sensory neurons and in a rat pheochromocytoma PC12 cell line. The ligand and...