C A Cartwright
Overview
Explore the profile of C A Cartwright including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
1209
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Recent Articles
1.
Swaminathan G, Cartwright C
Oncogene
. 2011 Jun;
31(3):376-89.
PMID: 21685945
E-cadherin and its cytoplasmic partners, catenins, mediate epithelial cell-cell adhesion. Disruption of this adhesion allows cancer cells to invade and metastasize. Aberrant activation of the Src tyrosine kinase disrupts cell-cell...
2.
Mamidipudi V, Cartwright C
Oncogene
. 2009 Sep;
28(50):4421-33.
PMID: 19767770
Earlier we showed that RACK1 regulates growth of human colon cells by suppressing Src activity at G(1) and mitotic checkpoints. Here, we show that RACK1 also induces apoptosis of the...
3.
Mamidipudi V, Dhillon N, Parman T, Miller L, Lee K, Cartwright C
Oncogene
. 2006 Oct;
26(20):2914-24.
PMID: 17072338
Previously, we showed that Src tyrosine kinases are activated early in the development of human colon cancer and are suppressed as intestinal cells differentiate. We identified RACK1 as an endogenous...
4.
Chang B, Chiang M, Cartwright C
J Biol Chem
. 2001 Mar;
276(23):20346-56.
PMID: 11279199
RACK1 is an intracellular receptor for the serine/ threonine protein kinase C. Previously, we demonstrated that RACK1 also interacts with the Src protein-tyrosine kinase. RACK1, via its association with these...
5.
Walter A, Peng Z, Cartwright C
Oncogene
. 1999 Apr;
18(11):1911-20.
PMID: 10208413
Previously, we demonstrated that the Src tyrosine kinase interacts with the Shp-2 tyrosine phosphatase. To determine whether Shp-2 regulates Src kinase activity, we measured Src activity in cells overexpressing wild-type...
6.
Chang B, Conroy K, Machleder E, Cartwright C
Mol Cell Biol
. 1998 Jun;
18(6):3245-56.
PMID: 9584165
To isolate and characterize proteins that interact with the unique domain and SH3 and SH2 domains of Src and potentially regulate Src activity, we used the yeast two-hybrid assay to...
7.
Kumble S, Omary M, Cartwright C, Triadafilopoulos G
Gastroenterology
. 1997 Feb;
112(2):348-56.
PMID: 9024288
Background & Aims: The neoplastic progression of Barrett's esophagus (BE) may involve genomic instability, inactivation of tumor suppressor genes, or activation of oncogenes. Because activation of Src tyrosine kinase occurs...
8.
Peng Z, Cartwright C
Oncogene
. 1995 Nov;
11(10):1955-62.
PMID: 7478513
The specific activity of the Src tyrosine kinase is elevated in human colon carcinoma cells. To identify Src-binding proteins that might upregulate Src activity in these cells, a human colon...
9.
Park J, Cartwright C
Mol Cell Biol
. 1995 May;
15(5):2374-82.
PMID: 7739521
Src and Yes protein-tyrosine kinase activities are elevated in malignant and premalignant tumors of the colon. To determine whether Src activity is elevated throughout the human colon carcinoma cell cycle...
10.
Pena S, Melhem M, Meisler A, Cartwright C
Gastroenterology
. 1995 Jan;
108(1):117-24.
PMID: 7806032
Background/aims: The cellular oncogene c-yes and its viral homologue v-yes (the transforming gene of Yamaguchi 73 and Esh avian sarcoma viruses) encode 62-kilodalton, cytoplasmic, membrane-associated, protein-tyrosine kinases. For the related...