C A Alper
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Explore the profile of C A Alper including associated specialties, affiliations and a list of published articles.
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227
Citations
3838
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Recent Articles
1.
Raum D, Balner H, Petersen B, Alper C
Immunogenetics
. 2012 Mar;
10(5):455-68.
PMID: 22457919
Significant polymorphism of serum complement components Bf, C2, C3, C6, and C8 in the chimpanzee has been demonstrated. The data are consistent with the hypothesis that C2 and Bf are...
2.
Bilbao J, Calvo B, Aransay A, Martin-Pagola A, Perez de Nanclares G, Aly T, et al.
Genes Immun
. 2006 Aug;
7(7):550-4.
PMID: 16929349
The major susceptibility locus for type 1 diabetes mellitus (T1D) maps to the human lymphocyte antigen (HLA) class II region in the major histocompatibility complex on chromosome 6p21. In southern...
3.
Pinto C, Smith A, LARSEN C, Fernandez-Vina M, Husain Z, Clavijo O, et al.
Hum Immunol
. 2004 Feb;
65(2):181-7.
PMID: 14969773
The associations of HLA-B*4402 and HLA-B*4403 with alleles of HLA-A and HLA-Cw were investigated in panels of HLA-B*4403 and HLA-B*4402 homozygous individuals and in selected individuals carrying HLA-Cw*04 and HLA-B*4403....
4.
Yunis E, LARSEN C, Fernandez-Vina M, Awdeh Z, Romero T, Hansen J, et al.
Tissue Antigens
. 2003 Jul;
62(1):1-20.
PMID: 12859592
The difference in sizes of conserved stretches of DNA sequence within the major histocompatibility complex (MHC) in human individuals constitutes an underappreciated genetic diversity that has many practical implications. We...
5.
Uko G, Fraser P, Awdeh Z, Fici D, Crawford K, LARSEN C, et al.
Genes Immun
. 2001 Apr;
2(1):11-9.
PMID: 11294562
We demonstrate activation of primary human TCRBV-specific CD4+ cells in vitro towards hepatitis B surface antigen (HBsAg) and tetanus toxoid (TT) without the use of cell lines, clones or added...
6.
Crawford K, Alper C
Rev Immunogenet
. 2001 Mar;
2(3):323-38.
PMID: 11256743
After a brief history of complement genetics, general considerations and applications to our understanding of immune function, evolution, population structure and migration and forensic medicine, selected topics in complement genetics...
7.
Alper C, Awdeh Z, Kruskall M, Eisenbarth G, Brink S, Katz A, et al.
Tissue Antigens
. 2000 Oct;
56(3):207-16.
PMID: 11034556
The extended major histocompatibility complex (MHC) haplotype [HLA-B8, SC01, DR3] is increased in frequency among patients with immunoglobulin (Ig)A deficiency and common variable immunodeficiency. Because the genomic region from HLA-B...
8.
Alper C, Awdeh Z
Tissue Antigens
. 2000 Oct;
56(3):199-206.
PMID: 11034555
We propose an approach to understanding incomplete penetrance of disease susceptibility genes as a method of studying the underlying mechanisms of polygenic diseases. Incomplete penetrance is the failure of genetically...
9.
Calvo B, Castano L, Fici D, Awdeh Z, Alper C
J Clin Immunol
. 2000 Aug;
20(3):216-20.
PMID: 10941830
We showed previously that the conserved extended MHC haplotype [HLA-B8, SCO1, DR3] carries recessive susceptibility genes for IgA and IgG4 deficiency and dominant genes for IgD and IgG3 deficiency. [HLA-B18,...
10.
Alper C, Dubey D, Yunis E, Awdeh Z
Exp Clin Immunogenet
. 2000 Jul;
17(3):138-47.
PMID: 10899739
We wished to determine the frequencies of the MHC and non-MHC susceptibility genes for polygenic autoimmune diseases like type 1 diabetes (IDDM). We used Mendelian inheritance and the Hardy-Weinberg equilibrium...