Buford L Nichols
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Explore the profile of Buford L Nichols including associated specialties, affiliations and a list of published articles.
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43
Citations
645
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Recent Articles
1.
Hayes A, Swackhamer C, Quezada-Calvillo R, Butte N, Sterchi E, Nichols B, et al.
Eur J Nutr
. 2025 Feb;
64(2):83.
PMID: 39904882
Purpose: Superior metabolic flexibility, or the ability to efficiently switch between oxidation of carbohydrate and fat, is inversely associated with obesity and type 2 diabetes. The influence of dietary factors...
2.
Nichols B, Baker R, Baker S
JPGN Rep
. 2023 May;
2(1):e027.
PMID: 37206939
Human breath is an easily, noninvasively obtained substance. It offers insight into metabolism and is used to diagnose disaccharide malabsorption, infection, small bowel bacterial over growth, and transit times. Herein,...
3.
Wasuwanich P, Choudry H, Ingviya T, Scheimann A, AuYeung K, Karwowski C, et al.
BMC Gastroenterol
. 2020 Oct;
20(1):331.
PMID: 33036568
Background: Disaccharides such as lactose and sucrose are sugars commonly found in human diet. They are broken down by mucosal disaccharidases in the duodenum. Previous small studies found no associations...
4.
Hasek L, Avery S, Chacko S, Fraley J, Vohra F, Quezada-Calvillo R, et al.
Nutrition
. 2020 Jun;
78:110857.
PMID: 32599415
Objectives: Maltase-glucoamylase (Mgam) and sucrase-isomaltase (Si) are mucosal α-glucosidases required for the digestion of starch to glucose. We hypothesized that a dietary approach to reduce Mgam and Si activities can...
5.
de Laffolie J, Sheridan D, Reinshagen K, Wessel L, Zimmermann C, Stricker S, et al.
FASEB J
. 2020 Jan;
34(3):3983-3995.
PMID: 31957074
Background And Aims: Intestinal adaptation in short bowel syndrome (SBS) includes morphologic processes and functional mechanisms. This study investigated whether digestive enzyme expression in the duodenum and colon is upregulated...
6.
7.
Robayo-Torres C, Diaz-Sotomayor M, Hamaker B, Baker S, Chumpitazi B, Opekun A, et al.
J Pediatr Gastroenterol Nutr
. 2018 May;
66 Suppl 3:S61-S64.
PMID: 29762381
Background And Hypotheses: Human starch digestion is a multienzyme process involving 6 different enzymes: salivary and pancreatic α-amylase; sucrase and isomaltase (from sucrose-isomaltase [SI]), and maltase and glucoamylase (from maltase-glucoamylase...
8.
Chumpitazi B, Robayo-Torres C, Tsai C, Opekun A, Baker S, Nichols B, et al.
J Pediatr Gastroenterol Nutr
. 2018 May;
66 Suppl 3:S52-S55.
PMID: 29762379
Background: A subset of children with functional gastrointestinal disorders (FGIDs), which includes functional dyspepsia, may have duodenal disaccharidase deficiencies. Objectives: To determine the frequency, demographics, and clinical characteristics associated with...
9.
Nichols B, Baker S, Quezada-Calvillo R
J Pediatr Gastroenterol Nutr
. 2018 May;
66 Suppl 3:S24-S29.
PMID: 29762372
The mucosal maltase enzymes are characterized by an activity that produces glucose from linear glucose polymers, assayed with the disaccharide maltose. The related enzyme isomaltase produces glucose from branched glucose...
10.
Chegeni M, Amiri M, Nichols B, Naim H, Hamaker B
FASEB J
. 2018 Feb;
32(7):3903-3911.
PMID: 29465310
Dietary starch is finally converted to glucose for absorption by the small intestine mucosal α-glucosidases (sucrase-isomaltase [SI] and maltase-glucoamylase), and control of this process has health implications. Here, the molecular...