Bryce J Carpenter
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Explore the profile of Bryce J Carpenter including associated specialties, affiliations and a list of published articles.
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8
Citations
108
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Recent Articles
1.
Hauck A, Mehmood R, Carpenter B, Frankfurter M, Tackenberg M, Inoue S, et al.
Nat Metab
. 2024 Apr;
6(5):825-836.
PMID: 38622413
Nuclear receptor corepressors (NCoRs) function in multiprotein complexes containing histone deacetylase 3 (HDAC3) to alter transcriptional output primarily through repressive chromatin remodelling at target loci. In the liver, loss of...
2.
Latimer M, Williams L, Shanmugan G, Carpenter B, Lazar M, Dierickx P, et al.
Commun Biol
. 2023 Nov;
6(1):1149.
PMID: 37952007
Circadian disruption increases cardiovascular disease (CVD) risk, through poorly understood mechanisms. Given that small RNA species are critical modulators of cardiac physiology/pathology, we sought to determine the extent to which...
3.
Dierickx P, Carpenter B, Celwyn I, Kelly D, Baur J, Lazar M
Front Mol Med
. 2023 Jun;
2.
PMID: 37389009
The REV-ERB nuclear receptors are key components of the circadian clock. Loss of REV-ERBs in the mouse heart causes dilated cardiomyopathy and premature lethality. This is associated with a marked...
4.
Carpenter B, Dierickx P
Am J Physiol Cell Physiol
. 2022 Sep;
323(4):C1168-C1176.
PMID: 36062878
Nicotinamide adenine dinucleotide (NAD) is a critical redox factor and coenzyme with rhythmic availability, and reduced NAD levels are a common factor in many disease states, including risk factors associated...
5.
Circadian REV-ERBs repress to activate NAMPT-dependent NAD biosynthesis and sustain cardiac function
Dierickx P, Zhu K, Carpenter B, Jiang C, Vermunt M, Xiao Y, et al.
Nat Cardiovasc Res
. 2022 Jan;
1(1):45-58.
PMID: 35036997
The heart is a highly metabolic organ that uses multiple energy sources to meet its demand for ATP production. Diurnal feeding-fasting cycles result in substrate availability fluctuations which, together with...
6.
Adlanmerini M, Krusen B, Nguyen H, Teng C, Woodie L, Tackenberg M, et al.
Sci Adv
. 2021 Oct;
7(44):eabh2007.
PMID: 34705514
Circadian disruption, as occurs in shift work, is associated with metabolic diseases often attributed to a discordance between internal clocks and environmental timekeepers. REV-ERB nuclear receptors are key components of...
7.
Adlanmerini M, Nguyen H, Krusen B, Teng C, Geisler C, Peed L, et al.
J Clin Invest
. 2020 Oct;
131(1).
PMID: 33021965
Obesity occurs when energy expenditure is outweighed by energy intake. Tuberal hypothalamic nuclei, including the arcuate nucleus (ARC), ventromedial nucleus (VMH), and dorsomedial nucleus (DMH), control food intake and energy...
8.
Adlanmerini M, Carpenter B, Remsberg J, Aubert Y, Peed L, Richter H, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(37):18691-18699.
PMID: 31451658
Ambient temperature influences the molecular clock and lipid metabolism, but the impact of chronic cold exposure on circadian lipid metabolism in thermogenic brown adipose tissue (BAT) has not been studied....