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Bryan Z Wang

Explore the profile of Bryan Z Wang including associated specialties, affiliations and a list of published articles. Areas
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Citations 35
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Recent Articles
1.
Wang B, Morsink M, Kim S, Luo L, Zhang X, Soni R, et al.
J Clin Invest . 2025 Jan; 135(1). PMID: 39744939
Loss of Bcl2-associated athanogene 3 (BAG3) is associated with dilated cardiomyopathy (DCM). BAG3 regulates sarcomere protein turnover in cardiomyocytes; however, the function of BAG3 in other cardiac cell types is...
2.
Kim Y, Wang K, Lock R, Nash T, Fleischer S, Wang B, et al.
IEEE Open J Eng Med Biol . 2024 Apr; 5:238-249. PMID: 38606403
Contractile response and calcium handling are central to understanding cardiac function and physiology, yet existing methods of analysis to quantify these metrics are often time-consuming, prone to mistakes, or require...
3.
Wang B, Nash T, Zhang X, Rao J, Abriola L, Kim Y, et al.
Cell Rep Med . 2023 Mar; 4(3):100976. PMID: 36921598
Restrictive cardiomyopathy (RCM) is defined as increased myocardial stiffness and impaired diastolic relaxation leading to elevated ventricular filling pressures. Human variants in filamin C (FLNC) are linked to a variety...
4.
Zhang X, Wang B, Kim M, Nash T, Liu B, Rao J, et al.
Cell Rep . 2022 Aug; 40(7):111203. PMID: 35977512
In the heart, protein kinase A (PKA) is critical for activating calcium handling and sarcomeric proteins in response to beta-adrenergic stimulation leading to increased myocardial contractility and performance. The catalytic...
5.
Wang B, Luo L, Vunjak-Novakovic G
Adv Healthc Mater . 2021 Oct; 11(5):e2101557. PMID: 34706168
Extracellular vesicles (EVs) are carriers of biological signals through export and delivery of RNAs and proteins. Of increasing interest is the use of EVs as a platform for delivery of...
6.
Parsa H, Wang B, Vunjak-Novakovic G
Lab Chip . 2017 Aug; 17(19):3264-3271. PMID: 28832065
Current in vitro models fall short in deciphering the mechanisms of cardiac hypertrophy induced by volume overload. We developed a pneumatic microfluidic platform for high-throughput studies of cardiac hypertrophy that...