Bryan T Phillips
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Explore the profile of Bryan T Phillips including associated specialties, affiliations and a list of published articles.
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20
Citations
383
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Recent Articles
1.
Wolf A, Adams-Phillips L, Adams A, Erives A, Phillips B
Cells Dev
. 2025 Feb;
:204013.
PMID: 40010690
β-catenin is a highly conserved multifunctional protein capable of mediating cell adhesion via E-cadherin and transactivation of target genes of the canonical Wnt signaling pathway. The nematode, C. elegans contains...
2.
Michel M, Phillips B
Mol Biol Cell
. 2025 Jan;
36(3):ar25.
PMID: 39813084
Asymmetric cell division (ACD) allows daughter cells of a polarized mother to acquire different developmental fates. In , the Wnt/β-catenin Asymmetry (WβA) pathway regulates many embryonic and larval ACDs; here,...
3.
Michel M, Phillips B
bioRxiv
. 2023 Jul;
PMID: 37503055
Asymmetric cell division (ACD) allows daughter cells of a polarized mother to acquire different developmental fates. In , the Wnt/β-catenin Asymmetry (WβA) pathway oversees many embryonic and larval ACDs; here,...
4.
Thompson J, Michel M, Phillips B
Mol Biol Cell
. 2022 Feb;
33(5):ar42.
PMID: 35196020
The Wnt/β-catenin asymmetry (WβA) pathway utilizes asymmetric regulation of SYS-1/β-catenin and POP-1/TCF coactivators. WβA differentially regulates gene expression during cell fate decisions, specifically by asymmetric localization of determinants in mother...
5.
Fassler J, Skuodas S, Weeks D, Phillips B
J Mol Biol
. 2021 Aug;
433(21):167215.
PMID: 34450138
Protein aggregation is a feature of numerous neurodegenerative diseases. However, regulated, often reversible, formation of protein aggregates, also known as condensates, helps control a wide range of cellular activities including...
6.
7.
Vora S, Fassler J, Phillips B
Mol Biol Cell
. 2020 Jun;
31(17):1951-1961.
PMID: 32583737
The Wnt/β-catenin signaling pathway is central to metazoan development and routinely dysregulated in cancer. Wnt/β-catenin signaling initiates transcriptional reprogramming upon stabilization of the transcription factor β-catenin, which is otherwise posttranslationally...
8.
Skuodas S, Clemons A, Hayes M, Goll A, Zora B, Weeks D, et al.
Mol Biol Cell
. 2020 Apr;
31(13):1324-1345.
PMID: 32320318
Protein aggregation, once believed to be a harbinger and/or consequence of stress, age, and pathological conditions, is emerging as a novel concept in cellular regulation. Normal versus pathological aggregation may...
9.
Lam A, Phillips B
Results Probl Cell Differ
. 2017 Apr;
61:83-114.
PMID: 28409301
Asymmetric cell division is a common mode of cell differentiation during the invariant lineage of the nematode, C. elegans. Beginning at the four-cell stage, and continuing throughout embryogenesis and larval...
10.
Vora S, Phillips B
Cell Cycle
. 2016 Jun;
15(16):2124-2134.
PMID: 27294844
The centrosome is the major microtubule-organizing center in animal cells but is dispensable for proper microtubule spindle formation in many biological contexts and is thus thought to fulfill additional functions....