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Bryan Ericksen

Explore the profile of Bryan Ericksen including associated specialties, affiliations and a list of published articles. Areas
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Citations 517
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Recent Articles
1.
Raines K, Agarwal P, Augustijns P, Alayoubi A, Attia L, Bauer-Brandl A, et al.
AAPS J . 2023 Nov; 25(6):103. PMID: 37936002
The in-person workshop "Drug Dissolution in Oral Drug Absorption" was held on May 23-24, 2023, in Baltimore, MD, USA. The workshop was organized into lectures and breakout sessions. Three common...
2.
Ericksen B
F1000Res . 2023 Jun; 11:933. PMID: 37360940
HNP1, LL-37, and HBD1 are antimicrobial against Escherichia coli ATCC 25922 at the standard inoculum but less active at higher inocula.   The virtual colony count (VCC) microbiological assay was adapted...
3.
Ericksen B
F1000Res . 2018 Feb; 4:1. PMID: 29333228
Dark blue rings and circles emerged when the non-specific polysaccharide stain lactophenol cotton blue was added to Gram stained slides. The dark blue staining is attributable to the presence of...
4.
Ericksen B
F1000Res . 2015 Feb; 3:267. PMID: 25671086
The virtual colony count (VCC) microbiological assay has been utilized for over a decade to measure the antimicrobial activity of peptides such as defensins and LL-37 against biosafety level (BSL)-1...
5.
Zhao L, Tolbert W, Ericksen B, Zhan C, Wu X, Yuan W, et al.
PLoS One . 2013 Nov; 8(11):e78937. PMID: 24236072
HNP1 is a human alpha defensin that forms dimers and multimers governed by hydrophobic residues, including Tyr¹⁶, Ile²⁰, Leu²⁵, and Phe²⁸. Previously, alanine scanning mutagenesis identified each of these residues...
6.
Pazgier M, Ericksen B, Ling M, Toth E, Shi J, Li X, et al.
Biochemistry . 2013 Feb; 52(9):1547-58. PMID: 23406372
Cathelicidins form a family of small host defense peptides distinct from another class of cationic antimicrobial peptides, the defensins. They are expressed as large precursor molecules with a highly conserved...
7.
Xu S, Li H, Shao X, Fan C, Ericksen B, Liu J, et al.
J Med Chem . 2012 Jul; 55(15):6881-7. PMID: 22780881
Dengue virus (DENV) infection is a serious public health threat worldwide that demands effective treatment. In the search for potent virus protease inhibitors, several cone snail venoms were screened against...
8.
Rajabi M, Ericksen B, Wu X, de Leeuw E, Zhao L, Pazgier M, et al.
J Biol Chem . 2012 May; 287(26):21615-27. PMID: 22573326
Human α-defensins are cationic peptides that self-associate into dimers and higher-order oligomers. They bind protein toxins, such as anthrax lethal factor (LF), and kill bacteria, including Escherichia coli and Staphylococcus...
9.
Zhao L, Ericksen B, Wu X, Zhan C, Yuan W, Li X, et al.
J Biol Chem . 2012 Apr; 287(23):18900-12. PMID: 22496447
The human α-defensins (HNP) are synthesized in vivo as inactive prodefensins, and contain a conserved glycine, Gly(17), which is part of a β-bulge structure. It had previously been shown that...
10.
Pazgier M, Wei G, Ericksen B, Jung G, Wu Z, de Leeuw E, et al.
J Biol Chem . 2012 Jan; 287(12):8944-53. PMID: 22270360
Human myeloid α-defensins called HNPs play multiple roles in innate host defense. The Trp-26 residue of HNP1 was previously shown to contribute importantly to its ability to kill S. aureus,...