Bryan Coburn
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Explore the profile of Bryan Coburn including associated specialties, affiliations and a list of published articles.
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69
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2141
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Recent Articles
11.
Oliva M, Heirali A, Watson G, Rooney A, Cochrane K, Jennings S, et al.
Br J Cancer
. 2024 May;
130(12):1936-1942.
PMID: 38714747
Background: Gut microbiome modulation to boost antitumor immune responses is under investigation. Methods: ROMA-2 evaluated the microbial ecosystem therapeutic (MET)-4 oral consortia, a mixture of cultured human stool-derived immune-responsiveness associated...
12.
Genta S, Lajkosz K, Yee N, Spiliopoulou P, Heirali A, Hansen A, et al.
J Exp Clin Cancer Res
. 2023 Oct;
42(1):276.
PMID: 37865776
Background: Immune-checkpoint inhibitors (ICI) can lead to immune-related adverse events (irAEs) in a significant proportion of patients. The mechanisms underlying irAEs development are mostly unknown and might involve multiple immune...
13.
Salawu A, Wang B, Han M, Geady C, Heirali A, Berman H, et al.
Clin Cancer Res
. 2023 Aug;
29(20):4128-4138.
PMID: 37566240
Purpose: Non-inflamed (cold) tumors such as leiomyosarcoma do not benefit from immune checkpoint blockade (ICB) monotherapy. Combining ICB with angiogenesis or PARP inhibitors may increase tumor immunogenicity by altering the...
14.
Rooney A, Cochrane K, Fedsin S, Yao S, Anwer S, Dehmiwal S, et al.
mBio
. 2023 Jul;
14(4):e0348222.
PMID: 37404011
Intestinal colonization with pathogens and antimicrobial-resistant organisms (AROs) is associated with increased risk of infection. Fecal microbiota transplant (FMT) has successfully been used to cure recurrent infection (rCDI) and to...
15.
Heirali A, Moossavi S, Arrieta M, Coburn B
Open Forum Infect Dis
. 2023 May;
10(5):ofad195.
PMID: 37180590
Interactions between the microbiome and medical therapies are distinct and bidirectional. The existing term "pharmacomicrobiomics" describes the effects of the microbiome on drug distribution, metabolism, efficacy, and toxicity. We propose...
16.
Pang J, Raka F, Heirali A, Shao W, Liu D, Gu J, et al.
Nat Commun
. 2023 May;
14(1):2656.
PMID: 37160898
Two common features of dietary polyphenols have hampered our mechanistic understanding of their beneficial effects for decades: targeting multiple organs and extremely low bioavailability. We show here that resveratrol intervention...
17.
Elebyary O, Fine N, Sun C, Saha S, Robinson S, Mojdami Z, et al.
Clin Infect Dis
. 2023 May;
77(5):752-760.
PMID: 37157867
Background: Bloodstream infections (BSIs) are the most common infectious complication in patients who receive allogeneic hematopoietic stem-cell transplants (allo-HSCTs). Polymorphonuclear neutrophils (PMNs) are quantified to monitor the susceptibility to BSIs;...
18.
Armstrong E, Hemmerling A, Joag V, Huibner S, Kulikova M, Crawford E, et al.
Open Forum Infect Dis
. 2023 Feb;
10(1):ofad007.
PMID: 36726539
Background: Bacterial vaginosis (BV) is a proinflammatory genital condition associated with adverse reproductive health outcomes, including increased HIV incidence. However, BV recurrence rates are high after standard antibiotic treatment. While...
19.
Spiliopoulou P, Janse van Rensburg H, Avery L, Kulasingam V, Razak A, Bedard P, et al.
Cell Death Dis
. 2023 Jan;
14(1):49.
PMID: 36670100
Despite more than 2 years having elapsed since the onset of SARS-CoV-2 pandemic, a level of hesitation around increased SARS-CoV-2 vaccine toxicity in cancer patients receiving immunotherapy (IO) remains. This...
20.
Liu R, Armstrong E, Constable S, Buchanan L, Mohammadi A, Galiwango R, et al.
Am J Reprod Immunol
. 2023 Jan;
89(3):e13674.
PMID: 36593681
Problem: The genital epithelial barrier is a crucial first line of defence against HIV, and epithelial disruption may enhance HIV susceptibility. Assessment of genital epithelial integrity requires biopsies, but their...