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Bryan Coburn

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Articles 69
Citations 2141
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Recent Articles
1.
Zeng P, Lin R, Fung K, Khan H, Cecchini M, Woo E, et al.
EBioMedicine . 2025 Mar; 114:105631. PMID: 40048848
Background: The larynx consists of the supraglottis, glottis, and subglottis and each differ in tissue composition, lymphatic drainage, ability to counter infections, and response to injuries. However, the cellular mechanisms...
2.
Lin R, Zeng P, Fung K, Khan H, Cecchini M, Woo E, et al.
EBioMedicine . 2025 Mar; 114:105629. PMID: 40048847
Background: First described in 1972, idiopathic subglottic stenosis (iSGS) is a serious chronic orphan disease characterised by recurrent scarring of the subglottis. Although the cause is unknown, iSGS is almost...
3.
Armstrong E, Liu R, Pollock J, Huibner S, Udayakumar S, Irungu E, et al.
Microbiome . 2025 Feb; 13(1):39. PMID: 39905573
Background: The composition of the vaginal microbiota is closely linked to adverse sexual and reproductive health outcomes, due in part to effects on genital immunology. Compositional approaches such as metagenomic...
4.
Liu R, Galiwango R, Park D, Huibner S, Aziz M, Anok A, et al.
Microbiome . 2025 Jan; 13(1):29. PMID: 39881368
Background: Genital inflammation increases HIV susceptibility and is associated with the density of pro-inflammatory anaerobes in the vagina and coronal sulcus. The penile urethra is a critical site of HIV...
5.
Carroll A, Mortimer L, Ghosh H, Reuter S, Grundmann H, Brinda K, et al.
Microbiol Spectr . 2024 Nov; 13(1):e0136624. PMID: 39611823
Importance: Urinary tract infections (UTIs) are a common diagnosis in hospitals and are often treated empirically with broad-spectrum antibiotics. These broad-spectrum agents can select for resistance in these bacteria and...
6.
Daneman N, Rishu A, Pinto R, Rogers B, Rogers B, Shehabi Y, et al.
N Engl J Med . 2024 Nov; 392(11):1065-1078. PMID: 39565030
Background: Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. Methods: In a multicenter, noninferiority trial, we...
7.
Liu R, Pollock J, Huibner S, Udayakumar S, Irungu E, Ngurukiri P, et al.
J Immunol . 2024 Sep; 213(10):1516-1527. PMID: 39345194
Bacteria-Ig interactions maintain homeostasis in the gut through the clearance of pathogenic bacteria and the development of immune tolerance to inflammatory bacteria; whether similar interactions modulate inflammation and bacterial colonization...
8.
Beckers M, Coburn B, Kalia L, Bloem B
J Parkinsons Dis . 2024 Jul; 14(5):913-915. PMID: 38968058
No abstract available.
9.
Armstrong E, Hemmerling A, Miller S, Huibner S, Kulikova M, Liu R, et al.
Microbiol Spectr . 2024 Jun; 12(8):e0350123. PMID: 38912808
Vaginal colonization by fungi may elicit genital inflammation and enhance the risk of adverse reproductive health outcomes, such as HIV acquisition. Cross-sectional studies have linked fungi with an absence of...
10.
Armstrong E, Hemmerling A, Miller S, Huibner S, Kulikova M, Crawford E, et al.
Microbiome . 2024 Jun; 12(1):110. PMID: 38907268
Background: Bacterial vaginosis (BV) increases HIV acquisition risk, potentially by eliciting genital inflammation. After BV treatment, the vaginal administration of LACTIN-V, a live biotherapeutic containing the Lactobacillus crispatus strain CTV-05,...