Bruce A Molitoris
Overview
Explore the profile of Bruce A Molitoris including associated specialties, affiliations and a list of published articles.
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Articles
154
Citations
7925
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Recent Articles
1.
Burmakin M, Gilmour P, Gram M, Shushakova N, Sandoval R, Molitoris B, et al.
Am J Physiol Renal Physiol
. 2024 May;
327(1):F103-F112.
PMID: 38779750
α-1-Microglobulin (A1M) is a circulating glycoprotein with antioxidant, heme-binding, and mitochondrial protection properties. The investigational drug RMC-035, a modified therapeutic A1M protein, was assessed for biodistribution and pharmacological activity in...
2.
Molitoris B, Dunn K, Sandoval R
Kidney Int
. 2023 Nov;
104(6):1065-1069.
PMID: 37981429
No abstract available.
3.
van Till J, Nojima H, Kameoka C, Hayashi C, Sakatani T, Washburn T, et al.
Kidney Int Rep
. 2023 Jul;
8(7):1407-1416.
PMID: 37441472
Introduction: Peroxisome proliferator-activated receptor δ (PPARδ) plays a central role in modulating mitochondrial function in ischemia-reperfusion injury. The novel PPARδ modulator, ASP1128, was evaluated. Methods: A randomized, double-blind, placebo-controlled, biomarker...
4.
Molitoris B, Wagner M
Clin J Am Soc Nephrol
. 2023 Mar;
18(9):1222-1224.
PMID: 36942999
No abstract available.
5.
Wagner M, Sandoval R, Yadav S, Campos S, Rhodes G, Phillips C, et al.
Kidney360
. 2023 Feb;
4(5):591-605.
PMID: 36848531
No abstract available.
6.
Bryniarski M, Sandoval R, Ruszaj D, Fraser-McArthur J, Yee B, Yacoub R, et al.
Mol Pharm
. 2023 Jan;
20(2):987-996.
PMID: 36626167
Despite the understanding that renal clearance is pivotal for driving the pharmacokinetics of numerous therapeutic proteins and peptides, the specific processes that occur following glomerular filtration remain poorly defined. For...
7.
Datta-Mannan A, Molitoris B, Feng Y, Martinez M, Sandoval R, Brown R, et al.
Drug Metab Dispos
. 2022 Dec;
51(3):403-412.
PMID: 36460476
Bifunctional antibody (BfAb) therapeutics offer the potential for novel functionalities beyond those of the individual monospecific entities. However, combining these entities into a single molecule can have unpredictable effects, including...
8.
Yu A, Zhao J, Peng W, Yadav S, Molitoris B, Wagner M, et al.
Proteomics Clin Appl
. 2022 Oct;
17(2):e2200063.
PMID: 36189891
Purpose: Chronic kidney disease (CKD) is defined by a reduced renal function, that is, glomerular filtration rate, and the extent of kidney damage is assessed by determining serum creatinine levels...
9.
Rosin D, Hall J, Zheng S, Huang L, Campos-Bilderback S, Sandoval R, et al.
Front Med (Lausanne)
. 2022 Aug;
9:931293.
PMID: 35966871
Adenosine triphosphate (ATP) released from injured or dying cells is a potent pro-inflammatory "danger" signal. Alkaline phosphatase (AP), an endogenous enzyme that de-phosphorylates extracellular ATP, likely plays an anti-inflammatory role...
10.
Dunn K, Hall A, Molitoris B
Front Physiol
. 2022 May;
13:891526.
PMID: 35586716
No abstract available.