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Brigit den Adel

Explore the profile of Brigit den Adel including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 226
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Recent Articles
1.
van Eldik W, den Adel B, Monshouwer-Kloots J, Salvatori D, Maas S, van der Made I, et al.
PLoS One . 2017 Dec; 12(12):e0189139. PMID: 29206857
Aims: The Z-disc is a crucial structure of the sarcomere and is implicated in mechanosensation/transduction. Dysregulation of Z-disc proteins often result in cardiomyopathy. We have previously shown that the Z-disc...
2.
Segers F, den Adel B, Bot I, van der Graaf L, van der Veer E, Gonzalez W, et al.
Arterioscler Thromb Vasc Biol . 2013 Jun; 33(8):1812-9. PMID: 23744990
Objective: In search of molecular imaging modalities for specific detection of inflammatory atherosclerotic plaques, we explored the potential of targeting scavenger receptor-AI (SR-AI), which is highly expressed by lesional macrophages...
3.
Hoefer I, den Adel B, Daemen M
Cardiovasc Res . 2013 Apr; 99(2):276-83. PMID: 23580605
Haemodynamic factors influence all forms of vascular growth (vasculogenesis, angiogenesis, arteriogenesis). Because of its prominent role in atherosclerosis, shear stress has gained particular attention, but other factors such as circumferential...
4.
den Adel B, van der Graaf L, Strijkers G, Lamb H, Poelmann R, van der Weerd L
PLoS One . 2013 Mar; 8(3):e57299. PMID: 23472079
Background: High-resolution contrast-enhanced imaging of the murine atherosclerotic vessel wall is difficult due to unpredictable flow artifacts, motion of the thin artery wall and problems with flow suppression in the...
5.
den Adel B, Daemen M, Poelmann R, van der Weerd L
Arterioscler Thromb Vasc Biol . 2013 Feb; PMID: 23413424
Recent advances in molecular resonance imaging of atherosclerosis enable to visualize atherosclerotic plaques in vivo using molecular targeted contrast agents. This offers opportunities to study atherosclerosis development and plaque vulnerability...
6.
den Adel B, van der Graaf L, Que I, Strijkers G, Lowik C, Poelmann R, et al.
Contrast Media Mol Imaging . 2012 Oct; 8(1):63-71. PMID: 23109394
The use of contrast-enhanced MRI to enable in vivo specific characterization of atherosclerotic plaques is increasing. In this study the intrinsic ability of two differently sized gadolinium-based contrast agents to...
7.
den Adel B, Bovens S, te Boekhorst B, Strijkers G, Poelmann R, van der Weerd L, et al.
Atherosclerosis . 2012 Aug; 225(2):274-80. PMID: 22882907
MRI using targeted contrast agents (CA) has emerged as a promising technique to study atherothrombotic disease in vivo. Particularly, the use of targeted Gd and lipid-based nanoparticles has enabled detailed...
8.
Verhaart I, van Duijn R, den Adel B, Roest A, Verschuuren J, Aartsma-Rus A, et al.
Neuromuscul Disord . 2012 Jan; 22(5):418-26. PMID: 22209498
Lack of dystrophin results in skeletal muscle dystrophy and dilated cardiomyopathy in humans and animal models. To achieve a basic understanding of the natural development of cardiomyopathy in different dystrophinopathy...
9.
Hessel M, Steendijk P, den Adel B, Schutte C, van der Laarse A
Cell Physiol Biochem . 2009 Aug; 24(3-4):201-10. PMID: 19710535
Background: We investigated whether (1) monocrotaline(MCT)-induced right ventricular (RV) dilatation is associated with re-expression of myocardial tenascin-C (TNC), (2) elevated plasma TNC levels can be used as a marker of...
10.
Umar S, Bax J, Klok M, van Bommel R, Hessel M, den Adel B, et al.
Eur J Heart Fail . 2008 Sep; 10(9):878-83. PMID: 18768351
Background: In patients with heart failure cardiac resynchronization therapy (CRT) leads to reverse ventricular remodelling. Aim: To evaluate whether myocardial collagen metabolism in patients with heart failure is implicated in...