Brian T Murphy
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Explore the profile of Brian T Murphy including associated specialties, affiliations and a list of published articles.
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53
Citations
2144
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Recent Articles
1.
Do T, Van Trinh T, Phi T, Nguyen T, Vu T, Le T, et al.
Chem Biodivers
. 2024 Dec;
:e202402701.
PMID: 39697149
Analysis of an antimicrobial extract from the agar-based culture of the marine-derived actinomycete Streptomyces sp. G666 led to the isolation of three new shikimic acid derivatives, streptomine A-C (1-3), along...
2.
Tan J, Augustinovic M, Omar A, Lourenzon V, Krull N, Lopez X, et al.
ACS Omega
. 2024 Nov;
9(44):44749-44759.
PMID: 39524626
We established a university-community partnership with the Boys and Girls Clubs of Chicago (BGCC)-named b-to involve middle school students in antibiotic discovery research. In the course of working with a...
3.
Paulo B, Recchia M, Lee S, Fergusson C, Romanowski S, Hernandez A, et al.
Chem Sci
. 2024 Sep;
PMID: 39309087
bacteria have emerged as a promising source of structurally diverse natural products that are expected to play important ecological and industrial roles. This order ranks in the top three in...
4.
Caro-Diaz E, Balunas M, Giddings L, Loesgen S, Murphy B, Naman C, et al.
J Nat Prod
. 2024 May;
87(5):1487-1492.
PMID: 38695619
Scientific conferences and meetings are valuable opportunities for researchers to network, communicate, and develop knowledge. For early career scientists, conferences can also be intimidating, confusing, and overwhelming, especially without having...
5.
Clark C, Hernandez A, Mullowney M, Fitz-Henley J, Li E, Romanowski S, et al.
ISME Commun
. 2023 Nov;
2(1):22.
PMID: 37938725
Microbial drug discovery programs rely heavily on accessing bacterial diversity from the environment to acquire new specialized metabolite (SM) lead compounds for the therapeutic pipeline. Therefore, knowledge of how commonly...
6.
Lee J, Ma R, Nguyen L, Khan S, Qader M, Mpofu E, et al.
ACS Infect Dis
. 2023 Jul;
9(8):1593-1601.
PMID: 37450563
For over a century, researchers have cultured microorganisms together on solid support─typically agar─in order to observe growth inhibition via antibiotic production. These simple bioassays have been critical to both academic...
7.
Nepomuceno V, Tylor K, Carlson S, Federle M, Murphy B, Perez Morales T
Microbiol Spectr
. 2023 Jun;
11(4):e0527922.
PMID: 37284782
Quorum sensing (QS) is a means of bacterial communication accomplished by microbe-produced signals and sensory systems. QS systems regulate important population-wide behaviors in bacteria, including secondary metabolite production, swarming motility,...
8.
Bergsten T, Li K, Lantvit D, Murphy B, Burdette J
Nutrients
. 2023 Mar;
15(6).
PMID: 36986136
Progesterone functions as a steroid hormone involved in female reproductive physiology. While some reproductive disorders manifest with symptoms that can be treated by progesterone or synthetic progestins, recent data suggest...
9.
Clark C, Nguyen L, Pham V, Sanchez L, Murphy B
Molecules
. 2022 Apr;
27(7).
PMID: 35408437
Libraries of microorganisms have served as a cornerstone of therapeutic drug discovery, though the continued re-isolation of known natural product chemical entities has remained a significant obstacle to discovery efforts....
10.
Li K, Diakite D, Austin J, Lee J, Lantvit D, Murphy B, et al.
J Nat Prod
. 2021 Dec;
85(1):237-247.
PMID: 34935393
Baicalein is a flavonoid extracted from the root of (Chinese skullcap) and is consumed as part of this botanical dietary supplement to reduce oxidative stress, pain, and inflammation. We previously...