Brian T Murphy
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Explore the profile of Brian T Murphy including associated specialties, affiliations and a list of published articles.
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53
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2144
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Recent Articles
11.
Austin J, Li K, Rivera Rodriguez R, Lantvit D, Murphy B, Burdette J
J Nat Prod
. 2021 Nov;
84(12):3090-3099.
PMID: 34813298
. (red clover) is a popular botanical supplement used for women's health. Irilone isolated from red clover previously demonstrated progestogenic potentiation activity. In this study, irilone enhanced progesterone signaling was...
12.
Elfeki M, Mantri S, Clark C, Green S, Ziemert N, Murphy B
ACS Chem Biol
. 2021 Oct;
16(11):2623-2631.
PMID: 34605624
Environmental microorganisms continue to serve as a major source of bioactive natural products (NPs) and as an inspiration for many other scaffolds in the toolbox of modern medicine. Nearly all...
13.
Lee J, Austin J, Burdette J, Murphy B
J Nat Prod
. 2021 Aug;
84(9):2612-2616.
PMID: 34411479
The use of botanical dietary supplements for the alleviation of conditions such as hot flashes, premenstrual syndrome, and fertility is prolific worldwide. Estrogen and progesterone receptors (ER and PR) and...
14.
Hernandez A, Nguyen L, Dhakal R, Murphy B
Nat Prod Rep
. 2020 Jul;
38(2):292-300.
PMID: 32706349
The question of whether culturable microorganisms will continue to be a viable source of new drug leads is inherently married to the strategies used to collect samples from the environment,...
15.
Condren A, Costa M, Sanchez N, Konkapaka S, Gallik K, Saxena A, et al.
Gut Microbes
. 2020 Mar;
11(4):1064-1076.
PMID: 32202200
There is a gap in measured microbial diversity when comparing genomic sequencing techniques versus cultivation from environmental samples in a laboratory setting. Standardized methods in artificial environments may not recapitulate...
16.
17.
Cao D, Van Trinh T, Doan Thi Mai H, Vu V, Le H, Thi Q, et al.
Mar Drugs
. 2019 Sep;
17(9).
PMID: 31510079
Three new lavandulylated flavonoids, (2,2'')-6-lavandulyl-7,4'-dimethoxy-5,2'-dihydroxylflavanone (), (2,2'')-6-lavandulyl-5,7,2',4'-tetrahydroxylflavanone (), and (2'')-5'-lavandulyl-2'-methoxy-2,4,4',6'-tetrahydroxylchalcone (), along with seven known compounds were isolated from culture broth of s sp. G248. Their structures were established by...
18.
Petrovich M, Ben Maamar S, Hartmann E, Murphy B, Poretsky R, Wells G
Microb Biotechnol
. 2019 Aug;
12(6):1324-1336.
PMID: 31410982
Wastewater treatment plants (WWTPs) contain high density and diversity of viruses which can significantly impact microbial communities in aquatic systems. While previous studies have investigated viruses in WWTP samples that...
19.
Costa M, Clark C, Omarsdottir S, Sanchez L, Murphy B
J Nat Prod
. 2019 Jul;
82(8):2167-2173.
PMID: 31335140
Libraries of microorganisms have been a cornerstone of drug discovery efforts since the mid-1950s, but strain duplication in some libraries has resulted in unwanted natural product redundancy. In the current...
20.
Clark C, Costa M, Conley E, Li E, Sanchez L, Murphy B
J Vis Exp
. 2019 Jun;
(147).
PMID: 31157770
In order to visualize the relationship between bacterial phylogeny and specialized metabolite production of bacterial colonies growing on nutrient agar, we developed IDBac-a low-cost and high-throughput matrix-assisted laser desorption/ionization time-of-flight...