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Brian Slingsby

Explore the profile of Brian Slingsby including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 19
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Recent Articles
1.
Abdi M, Beswick P, Billinton A, Chambers L, Charlton A, Collins S, et al.
Bioorg Med Chem Lett . 2010 Aug; 20(17):5080-4. PMID: 20673717
A computational lead-hopping exercise identified compound 4 as a structurally distinct P2X(7) receptor antagonist. Structure-activity relationships (SAR) of a series of pyroglutamic acid amide analogues of 4 were investigated and...
2.
Gleave R, Beswick P, Brown A, Giblin G, Haslam C, Livermore D, et al.
Bioorg Med Chem Lett . 2009 Oct; 19(23):6578-81. PMID: 19864133
2-Amino-5-aryl-pyridines, exemplified by compound 1, had been identified as a synthetically tractable series of CB(2) agonists from a high-throughput screen of the GlaxoSmithKline compound collection. Described herein are the results...
3.
Stefano G, Cadet P, Zhu W, Rialas C, Mantione K, Benz D, et al.
Neuro Endocrinol Lett . 2002 May; 23(2):85-93. PMID: 12011791
Through an extremely complicated equilibrium called homeostasis, all living organisms maintain their survival in the face of both externally and internally generated "stimuli". This apparent harmony is constantly challenged. Survival...