Brian P Dalrymple
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Explore the profile of Brian P Dalrymple including associated specialties, affiliations and a list of published articles.
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46
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1671
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Recent Articles
21.
Gu Q, Nagaraj S, Hudson N, Dalrymple B, Reverter A
BMC Genomics
. 2011 Jan;
12:23.
PMID: 21226902
Background: Gene regulation by transcription factors (TF) is species, tissue and time specific. To better understand how the genetic code controls gene expression in bovine muscle we associated gene expression...
22.
Ratnakumar A, Kirkness E, Dalrymple B
BMC Res Notes
. 2010 Dec;
3:334.
PMID: 21144002
Background: The sheep CHORI-243 bacterial artificial chromosome (BAC) library is being used in the construction of the virtual sheep genome, the sequencing and construction of the actual sheep genome assembly...
23.
Ratnakumar A, McWilliam S, Barris W, Dalrymple B
BMC Genomics
. 2010 Aug;
11:458.
PMID: 20678236
Background: The advent of cheap high through-put sequencing methods has facilitated low coverage skims of a large number of organisms. To maximise the utility of the sequences, assembly into contigs...
24.
Reverter A, Hudson N, Nagaraj S, Perez-Enciso M, Dalrymple B
Bioinformatics
. 2010 Feb;
26(7):896-904.
PMID: 20144946
Motivation: Although transcription factors (TF) play a central regulatory role, their detection from expression data is limited due to their low, and often sparse, expression. In order to fill this...
25.
Hudson N, Reverter A, Wang Y, Greenwood P, Dalrymple B
PLoS One
. 2009 Oct;
4(10):e7249.
PMID: 19794913
Background: Despite modern technologies and novel computational approaches, decoding causal transcriptional regulation remains challenging. This is particularly true for less well studied organisms and when only gene expression data is...
26.
Hudson N, Reverter A, Dalrymple B
PLoS Comput Biol
. 2009 May;
5(5):e1000382.
PMID: 19412532
Transcription factor (TF) regulation is often post-translational. TF modifications such as reversible phosphorylation and missense mutations, which can act independent of TF expression level, are overlooked by differential expression analysis....
27.
Tang D, Glazov E, McWilliam S, Barris W, Dalrymple B
BMC Genomics
. 2009 Apr;
10:188.
PMID: 19393063
Background: Detailed information regarding the number and organization of transfer RNA (tRNA) genes at the genome level is becoming readily available with the increase of DNA sequencing of whole genomes....
28.
Kijas J, Townley D, Dalrymple B, Heaton M, Maddox J, McGrath A, et al.
PLoS One
. 2009 Mar;
4(3):e4668.
PMID: 19270757
The genetic structure of sheep reflects their domestication and subsequent formation into discrete breeds. Understanding genetic structure is essential for achieving genetic improvement through genome-wide association studies, genomic selection and...
29.
Ratnakumar A, Barris W, McWilliam S, Brauning R, McEwan J, Snelling W, et al.
BMC Genomics
. 2009 Jan;
10:46.
PMID: 19166603
Background: In large genomics projects involving many different types of analyses of bacterial artificial chromosomes (BACs), such as fingerprinting, end sequencing (BES) and full BAC sequencing there are many opportunities...
30.
Waardenberg A, Reverter A, Wells C, Dalrymple B
BMC Syst Biol
. 2008 Oct;
2:88.
PMID: 18945372
Background: Myogenesis is an ordered process whereby mononucleated muscle precursor cells (myoblasts) fuse into multinucleated myotubes that eventually differentiate into myofibres, involving substantial changes in gene expression and the organisation...