Brian O Bodemann
Overview
Explore the profile of Brian O Bodemann including associated specialties, affiliations and a list of published articles.
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10
Citations
884
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Recent Articles
1.
Cooper J, Ou Y, McMillan E, Vaden R, Zaman A, Bodemann B, et al.
Cancer Res
. 2017 Jul;
77(18):5077-5094.
PMID: 28716898
Emerging observations link dysregulation of TANK-binding kinase 1 (TBK1) to developmental disorders, inflammatory disease, and cancer. Biochemical mechanisms accounting for direct participation of TBK1 in host defense signaling have been...
2.
Cooper J, Bodemann B, White M
Enzymes
. 2014 Jul;
34 Pt. B:137-56.
PMID: 25034103
Recognition that Ral guanine nucleotide exchange factors (RalGEFs) are direct Ras effectors and that Ral G-protein activation is a direct consequence of Ras activation has spurred focused efforts to establish...
3.
Ram R, Mendiratta S, Bodemann B, Torres M, Eskiocak U, White M
Mol Cell Biol
. 2014 Apr;
34(12):2350-8.
PMID: 24732797
The RASSF1A gene is one of the most frequently inactivated genes in over 30 different types of cancers (H. Donninger, M. D. Vos, and G. J. Clark, J. Cell Sci....
4.
Rifki O, Bodemann B, Battiprolu P, White M, Hill J
J Mol Cell Cardiol
. 2013 Mar;
59:128-38.
PMID: 23473774
Recent work has demonstrated that autophagy, a phylogenetically conserved, lysosome-mediated pathway of protein degradation, is a key participant in pathological cardiac remodeling. One common feature of cell growth and autophagy...
5.
Bodemann B, White M
Curr Biol
. 2013 Jan;
23(1):R17-20.
PMID: 23305663
Rare codons selectively limit the accumulation of Ras family member proteins with important consequences for Ras pathway activation and tumorigenesis.
6.
Bodemann B, Orvedahl A, Cheng T, Ram R, Ou Y, Formstecher E, et al.
Cell
. 2011 Jan;
144(2):253-67.
PMID: 21241894
The study of macroautophagy in mammalian cells has described induction, vesicle nucleation, and membrane elongation complexes as key signaling intermediates driving autophagosome biogenesis. How these components are recruited to nascent...
7.
Madigan J, Bodemann B, Brady D, Dewar B, Keller P, Leitges M, et al.
Biochem J
. 2009 Sep;
424(1):153-61.
PMID: 19723022
The Rnd proteins (Rnd1, Rnd2 and Rnd3/RhoE) form a distinct branch of the Rho family of small GTPases. Altered Rnd3 expression causes changes in cytoskeletal organization and cell cycle progression....
8.
Bodemann B, White M
Nat Rev Cancer
. 2008 Jan;
8(2):133-40.
PMID: 18219307
A confluence of recent observations has indicted the Ras-family G-proteins RALA and RALB as key offenders in the subversion of core biological systems driving oncogenic transformation. Here, we will focus...
9.
Whitehurst A, Bodemann B, Cardenas J, Ferguson D, Girard L, Peyton M, et al.
Nature
. 2007 Apr;
446(7137):815-9.
PMID: 17429401
Abundant evidence suggests that a unifying principle governing the molecular pathology of cancer is the co-dependent aberrant regulation of core machinery driving proliferation and suppressing apoptosis. Anomalous proteins engaged in...
10.
Bivona T, Quatela S, Bodemann B, Ahearn I, Soskis M, Mor A, et al.
Mol Cell
. 2006 Feb;
21(4):481-93.
PMID: 16483930
K-Ras associates with the plasma membrane (PM) through farnesylation that functions in conjunction with an adjacent polybasic sequence. We show that phosphorylation by protein kinase C (PKC) of S181 within...