» Authors » Brian M McDermott Jr

Brian M McDermott Jr

Explore the profile of Brian M McDermott Jr including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 26
Citations 508
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Kindig K, Stepanyan R, Kindt K, McDermott Jr B
Curr Biol . 2023 Mar; 33(7):1295-1307.e3. PMID: 36905930
In the lateral line system, water motion is detected by neuromast organs, fundamental units that are arrayed on a fish's surface. Each neuromast contains hair cells, specialized mechanoreceptors that convert...
2.
Gilbert B, Zhu S, Salameh A, Sun S, Alagramam K, McDermott Jr B
Front Cell Dev Biol . 2021 Dec; 9:709442. PMID: 34917607
To enable hearing, the sensory hair cell contains specialized subcellular structures at its apical region, including the actin-rich cuticular plate and circumferential band. ACF7 (actin crosslinking family protein 7), encoded...
3.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo W, et al.
Science . 2021 Dec; 374(6573):eabk0410. PMID: 34882480
Cytokinetic membrane abscission is a spatially and temporally regulated process that requires ESCRT (endosomal sorting complexes required for transport)–dependent control of membrane remodeling at the midbody, a subcellular organelle that...
4.
Bharadwaj T, Schrauwen I, Rehman S, Liaqat K, Acharya A, Giese A, et al.
Eur J Hum Genet . 2021 Jun; 30(1):22-33. PMID: 34135477
Hearing impairment (HI) is a common disorder of sensorineural function with a highly heterogeneous genetic background. Although substantial progress has been made in the understanding of the genetic etiology of...
5.
McDermott Jr B
Curr Biol . 2021 Apr; 31(7):R344-R347. PMID: 33848490
Fish use the highly stereotyped lateral line system to swim against a current. New research reveals that the order of the lateral line system is less important than brain response...
6.
Zhu S, Chen Z, Wang H, McDermott Jr B
Front Cell Dev Biol . 2021 Jan; 8:570486. PMID: 33490059
Hair cells are heterogenous, enabling varied roles in sensory systems. An emerging hypothesis is that the transmembrane channel-like (Tmc) proteins of the hair cell's mechanotransduction apparatus vary within and between...
7.
Gopal S, Lee Y, Stepanyan R, McDermott Jr B, Alagramam K
Proc Natl Acad Sci U S A . 2019 May; 116(22):11000-11009. PMID: 31097578
The pathogenic variant c.144T>G (p.N48K) in the clarin1 gene () results in progressive loss of vision and hearing in Usher syndrome IIIA (USH3A) patients. CLRN1 is predicted to be an...
8.
Vargo J, Walker S, Gopal S, Deshmukh A, McDermott Jr B, Alagramam K, et al.
Front Cell Neurosci . 2018 Jan; 11:393. PMID: 29311828
Cisplatin and other related platinum antineoplastic drugs are commonly used in the treatment of a variety of cancers in both adults and children but are often associated with severe side...
9.
Chou S, Chen Z, Zhu S, Davis R, Hu J, Liu L, et al.
Nat Commun . 2017 Dec; 8(1):2234. PMID: 29269857
Detection of water motion by the lateral line relies on mechanotransduction complexes at stereocilia tips. This sensory system is comprised of neuromasts, patches of hair cells with stereociliary bundles arranged...
10.
Chen Z, Chou S, McDermott Jr B
J Physiol . 2017 Nov; 596(3):409-421. PMID: 29086422
Key Points: The synaptic ribbon is an organelle that coordinates rapid and sustained vesicle release to enable hearing and balance. Ribeye a and b proteins are major constituents of the...