Brian M G Janssen
Overview
Explore the profile of Brian M G Janssen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
87
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wijdeven M, van Geel R, Hoogenboom J, Verkade J, Janssen B, Hurkmans I, et al.
MAbs
. 2022 May;
14(1):2078466.
PMID: 35634725
Antibody-drug conjugates (ADCs) are increasingly powerful medicines for targeted cancer therapy. Inspired by the trend to further improve their therapeutic index by generation of homogenous ADCs, we report here how...
2.
Verkade J, Wijdeven M, van Geel R, Janssen B, van Berkel S, van Delft F
Antibodies (Basel)
. 2019 Sep;
7(3).
PMID: 31544884
The conflict of interest section of the published paper [1] has been updated as follows[...].
3.
Verkade J, Wijdeven M, van Geel R, Janssen B, van Berkel S, van Delft F
Antibodies (Basel)
. 2019 Sep;
7(1).
PMID: 31544864
Despite tremendous efforts in the field of targeted cancer therapy with antibody-drug conjugates (ADCs), attrition rates have been high. Historically, the priority in ADC development has been the selection of...
4.
van Rosmalen M, Janssen B, Hendrikse N, van der Linden A, Pieters P, Wanders D, et al.
J Biol Chem
. 2016 Dec;
292(4):1477-1489.
PMID: 27974464
Meditopes are cyclic peptides that bind in a specific pocket in the antigen-binding fragment of a therapeutic antibody such as cetuximab. Provided their moderate affinity can be enhanced, meditope peptides...
5.
Janssen B, van Ommeren S, Merkx M
Int J Mol Sci
. 2015 Jun;
16(6):12631-47.
PMID: 26053396
The advancement of DNA-based bionanotechnology requires efficient strategies to functionalize DNA nanostructures in a specific manner with other biomolecules, most importantly peptides and proteins. Common DNA-functionalization methods rely on laborious...
6.
Janssen B, van Rosmalen M, van Beek L, Merkx M
Angew Chem Int Ed Engl
. 2015 Jan;
54(8):2530-3.
PMID: 25573528
Oligonucleotide-based molecular circuits offer the exciting possibility to introduce autonomous signal processing in biomedicine, synthetic biology, and molecular diagnostics. Here we introduce bivalent peptide-DNA conjugates as generic, noncovalent, and easily...
7.
Janssen B, Engelen W, Merkx M
ACS Synth Biol
. 2014 Sep;
4(5):547-53.
PMID: 25216042
DNA-templated reversible assembly of an enzyme-inhibitor complex is presented as a new and highly modular approach to control enzyme activity. TEM1-β-lactamase and its inhibitor protein BLIP were conjugated to different...
8.
Koay M, Janssen B, Merkx M
Dalton Trans
. 2012 Oct;
42(9):3230-2.
PMID: 23076326
We previously reported the development of high affinity Zn(2+) FRET sensors based on the Zn(2+)-mediated interaction between the CXXC motifs present in the copper chaperone proteins ATOX1 and WD4. By...