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Brian Lin

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Articles 75
Citations 3653
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Recent Articles
1.
Wolf M, Androulakis Korakakis P, Pinero A, Mohan A, Hermann T, Augustin F, et al.
PeerJ . 2025 Feb; 13:e18904. PMID: 39959841
Purpose: Resistance training using different ranges of motion may produce varying effects on musclular adaptations. The purpose of this study was to compare the effects of lengthened partial repetitions (LPs)...
2.
Gower M, Li X, Aguilar-Navarro A, Lin B, Fernandez M, Edun G, et al.
Sci Transl Med . 2025 Jan; 17(779):eadr2012. PMID: 39742502
T-lineage acute lymphoblastic leukemia (ALL) is an aggressive cancer comprising diverse subtypes that are challenging to stratify using conventional immunophenotyping. To gain insights into subset-specific therapeutic vulnerabilities, we performed an...
3.
Hajam I, Tsai C, Gonzalez C, Caldera J, Lazaro Diez M, Du X, et al.
Nat Commun . 2024 Dec; 15(1):10335. PMID: 39681568
Pathobionts have evolved many strategies to coexist with the host, but how immune evasion mechanisms contribute to the difficulty of developing vaccines against pathobionts is unclear. Meanwhile, Staphylococcus aureus (SA)...
4.
Tsai C, Hajam I, Caldera J, Chiang A, Gonzalez C, Du X, et al.
J Clin Invest . 2024 Dec; 134(24). PMID: 39680460
The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa modifies antibody activity is not clear. Herein, we demonstrate that...
5.
Waas M, Govindarajan M, Khoo A, Zuo C, Aastha A, He J, et al.
STAR Protoc . 2024 Oct; 5(4):103397. PMID: 39423124
Deep mass spectrometry-based proteomic profiling of rare cell populations has been constrained by sample input requirements. Here, we present a protocol for droplet-based one-pot preparation for proteomic samples (DROPPS), an...
6.
Criss S, Nguyen T, Gonzales S, Lin B, Kim M, Makres K, et al.
J Racial Ethn Health Disparities . 2024 Sep; PMID: 39259263
Background: Stigma and discrimination are associated with HIV persistence. Prior research has investigated the ability of ChatGPT to provide evidence-based recommendations, but the literature examining ChatGPT's performance across varied sociodemographic...
7.
Fumagalli S, Smith S, Ghazanchyan T, Meyer D, Paul R, Campbell C, et al.
BMC Bioinformatics . 2024 Sep; 25(1):294. PMID: 39242990
Mouse (Mus musculus) models have been heavily utilized in developmental biology research to understand mammalian embryonic development, as mice share many genetic, physiological, and developmental characteristics with humans. New explorations...
8.
Lek A, Atas E, Lin B, Hesterlee S, Abbott J, Byrne B, et al.
J Neuromuscul Dis . 2024 Aug; 11(5):1139-1160. PMID: 39121133
 This meeting report summarizes the presentations and discussions held at the summit on Challenges in Gene Therapy hosted by the Muscular Dystrophy Association (MDA) in 2023. Topics covered include safety...
9.
Kooistra T, Saez B, Roche M, Egea-Zorrilla A, Li D, Anketell D, et al.
bioRxiv . 2024 Jul; PMID: 38979172
Adult stem cells play a crucial role in tissue homeostasis and repair through multiple mechanisms. In addition to being able to replace aged or damaged cells, stem cells provide signals...
10.
Meddeb M, Koleini N, Jun S, Keykhaei M, Farshidfar F, Zhao L, et al.
bioRxiv . 2024 Jun; PMID: 38915649
Background: ATP-citrate lyase (ACLY) converts citrate into acetyl-CoA and oxaloacetate in the cytosol. It plays a prominent role in lipogenesis and fat accumulation coupled to excess glucose, and its inhibition...