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Brian H Ridgway

Explore the profile of Brian H Ridgway including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Forsyth T, Kearney P, Kim B, Johnson H, Aay N, Arcalas A, et al.
Bioorg Med Chem Lett . 2012 Nov; 22(24):7653-8. PMID: 23127890
We report the discovery of a series of 4-aryl-2-aminoalkylpyrimidine derivatives as potent and selective JAK2 inhibitors. High throughput screening of our in-house compound library led to the identification of hit...
2.
Larsen C, Ridgway B, Shaw J, Smith D, Woerpel K
J Am Chem Soc . 2005 Aug; 127(31):10879-84. PMID: 16076193
The factors controlling the highly alpha-selective C-glycosylation of ribose derivatives were determined by examining the stereoselective reactions of 18 ribose analogues differing in substitution at C-2, C-3, and C-4. The...
3.
Ridgway B, Woerpel K
J Org Chem . 2001 Oct; 63(3):458-460. PMID: 11672033
Deuterium-labeling experiments demonstrate that the transmetalation step of the Suzuki coupling reaction of alkylboranes and alpha-iodoenones proceeds with retention of stereochemistry.