Brian Fulton-Howard
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Explore the profile of Brian Fulton-Howard including associated specialties, affiliations and a list of published articles.
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17
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1167
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Recent Articles
1.
Bowles K, Pedicone C, Pugh D, Oja L, Sousa F, Keavey L, et al.
Cell Rep
. 2024 Nov;
43(12):115013.
PMID: 39602304
Due to the importance of 4R tau (with four microtubule-binding-repeat domains) in the pathogenicity of primary tauopathies, it has been challenging to model these diseases in induced pluripotent stem cell...
2.
Andrews S, Boeriu A, Belloy M, Renton A, Fulton-Howard B, Brenowitz W, et al.
Alzheimers Dement
. 2024 Oct;
20(12):8595-8604.
PMID: 39428957
Introduction: Evaluating the generalizability of dementia risk scores, primarily developed in non-Latinx White (NLW) participants, and interactions with genetic risk factors in diverse populations is crucial for addressing health disparities....
3.
Andrews S, Jonson C, Fulton-Howard B, Renton A, Yokoyama J, Yaffe K
medRxiv
. 2024 Jun;
PMID: 38903124
Importance: By integrating genetic and clinical risk factors into genomic-informed dementia risk reports, healthcare providers can offer patients detailed risk profiles to facilitate understanding of individual risk and support the...
4.
Andrews S, Boeriu A, Belloy M, Renton A, Fulton-Howard B, Brenowitz W, et al.
medRxiv
. 2024 May;
PMID: 38746455
Introduction: Evaluating the generalizability of dementia risk scores, primarily developed in non-Latinx White (NLW) participants, and interactions with genetic risk factors in diverse populations is crucial for addressing health disparities....
5.
Yu C, Bakshi A, Watts G, Renton A, Fulton-Howard B, Goate A, et al.
J Am Heart Assoc
. 2023 Nov;
12(21):e031459.
PMID: 37929782
Background The risk of atherosclerotic cardiovascular disease (ASCVD) increases sharply with age. Some older individuals, however, remain unaffected despite high predicted risk. These individuals may carry cardioprotective genetic variants that...
6.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, et al.
medRxiv
. 2023 Jul;
PMID: 37461624
Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in non-European ancestry groups in genome-wide association studies (GWAS). We constructed and analyzed a multi-ancestry GWAS dataset...
7.
Cochran J, Acosta-Uribe J, Esposito B, Madrigal L, Aguillon D, Giraldo M, et al.
Alzheimers Dement
. 2023 Mar;
19(9):3835-3847.
PMID: 36951251
Introduction: Genetic associations with Alzheimer's disease (AD) age at onset (AAO) could reveal genetic variants with therapeutic applications. We present a large Colombian kindred with autosomal dominant AD (ADAD) as...
8.
Andrews S, Renton A, Fulton-Howard B, Podlesny-Drabiniok A, Marcora E, Goate A
EBioMedicine
. 2023 Mar;
90:104511.
PMID: 36907103
Background: Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disorder and the most common form of dementia. AD is highly heritable, with heritability estimates of ∼70% from twin studies. Progressively...
9.
Bellenguez C, Kucukali F, Jansen I, Kleineidam L, Moreno-Grau S, Amin N, et al.
Nat Genet
. 2022 Apr;
54(4):412-436.
PMID: 35379992
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage...
10.
Farrell K, Kim S, Han N, Iida M, Gonzalez E, Otero-Garcia M, et al.
Acta Neuropathol
. 2021 Nov;
143(1):33-53.
PMID: 34719765
Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognitive...