Brian Chait
Overview
Explore the profile of Brian Chait including associated specialties, affiliations and a list of published articles.
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7
Citations
88
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Recent Articles
1.
Ge T, Brickner D, Zehr K, VanBelzen D, Zhang W, Caffalette C, et al.
Mol Cell
. 2025 Mar;
PMID: 40068679
Nuclear pore proteins (nucleoporins [Nups]) physically interact with hundreds of chromosomal sites, impacting transcription. In yeast, transcription factors mediate interactions between Nups and enhancers and promoters. To define the molecular...
2.
Ge T, Brickner D, Zehr K, VanBelzen D, Zhang W, Caffalette C, et al.
bioRxiv
. 2024 May;
PMID: 38798450
Nuclear pore proteins (Nups) in yeast, flies and mammals physically interact with hundreds or thousands of chromosomal sites, which impacts transcriptional regulation. In budding yeast, transcription factors mediate interaction of...
3.
Small G, Fedorova O, Olinares P, Chandanani J, Banerjee A, Choi Y, et al.
bioRxiv
. 2023 Oct;
PMID: 37808858
The enzymatic activity of the SARS-CoV-2 nidovirus RdRp-associated nucleotidyltransferase (NiRAN) domain is essential for viral propagation, with three distinct activities associated with modification of the nsp9 N-terminus, NMPylation, RNAylation, and...
4.
Manning J, Manning L, Dumoulin A, Padovan J, Chait B
Subcell Biochem
. 2020 Mar;
94:275-296.
PMID: 32189304
During the past two decades, significant advances have been made in our understanding of the human fetal and embryonic hemoglobins made possible by the availability of pure, highly characterized materials...
5.
Chase J, Catalano A, Noble A, Eng E, Olinares P, Molloy K, et al.
Elife
. 2018 Dec;
7.
PMID: 30582519
Assembly of bacterial ring-shaped hexameric replicative helicases on single-stranded (ss) DNA requires specialized loading factors. However, mechanisms implemented by these factors during opening and closing of the helicase, which enable...
6.
7.
Basu A, L Rose K, Zhang J, Beavis R, Ueberheide B, Garcia B, et al.
Proc Natl Acad Sci U S A
. 2009 Aug;
106(33):13785-90.
PMID: 19666589
Acetylation is a well-studied posttranslational modification that has been associated with a broad spectrum of biological processes, notably gene regulation. Many studies have contributed to our knowledge of the enzymology...
8.