Brian Bennett
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Explore the profile of Brian Bennett including associated specialties, affiliations and a list of published articles.
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117
Citations
1819
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Recent Articles
1.
Cheng J, Cheng M, Sinha S, Cely I, Charugundla S, Han M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060573
Background: Trimethylamine-N-oxide (TMAO) has been significantly linked to atherosclerosis via several mechanisms, but its direct effect on the atherosclerosis-prone vasculature remains unclear. The objective of this study was to characterize...
2.
Miller C, Knutson K, Liu D, Bennett B, Holz R
J Inorg Biochem
. 2024 Oct;
262:112763.
PMID: 39447484
A highly conserved second-sphere active site αSer residue in nitrile hydratase (NHase), that forms a hydrogen bond with the axial metal-bound water molecule, was mutated to Ala, Asp, and Thr,...
3.
Estes B, Jain M, Jia L, Whoriskey J, Bennett B, Hsu H
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927021
Through machine learning, identifying correlations between amino acid sequences of antibodies and their observed characteristics, we developed an internal viscosity prediction model to empower the rapid engineering of therapeutic antibody...
4.
Gerlich G, Miller C, Yang X, Diviesti K, Bennett B, Klein-Seetharaman J, et al.
J Biol Inorg Chem
. 2024 May;
29(4):427-439.
PMID: 38796812
Chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile; TPN) is an environmentally persistent fungicide that sees heavy use in the USA and is highly toxic to aquatic species and birds, as well as a probable human...
5.
Miller C, Huntoon D, Kaley N, Ogutu I, Fiedler A, Bennett B, et al.
J Inorg Biochem
. 2024 Apr;
256:112565.
PMID: 38677005
Two conserved second-sphere βArg (R) residues in nitrile hydratases (NHase), that form hydrogen bonds with the catalytically essential sulfenic and sulfinic acid ligands, were mutated to Lys and Ala residues...
6.
Wu H, Lv P, Wang J, Bennett B, Wang J, Li P, et al.
Elife
. 2024 Feb;
12.
PMID: 38372724
Epigenetic regulators present novel opportunities for both ischemic stroke research and therapeutic interventions. While previous work has implicated that they may provide neuroprotection by potentially influencing coordinated sets of genes...
7.
Chen Q, Malki S, Xu X, Bennett B, Lackford B, Kirsanov O, et al.
bioRxiv
. 2023 Oct;
PMID: 37873304
The foundation of spermatogenesis and lifelong fertility is provided by spermatogonial stem cells (SSCs). SSCs divide asymmetrically to either replenish their numbers (self-renewal) or produce undifferentiated progenitors that proliferate before...
8.
Lee J, Purello C, Booth S, Bennett B, Wiley C, Korstanje R
Geroscience
. 2023 Apr;
45(3):2079-2084.
PMID: 37079216
Chow diet is used in the majority of rodent studies and, although assumed to be standardized for dietary source and nutritional contents, it varies widely across commercial formulations. Similarly, current...
9.
Bajaj K, Andres S, Hofsommer D, Galib M, Mashuta M, Bennett B, et al.
Inorg Chem
. 2022 May;
61(20):7715-7719.
PMID: 35549215
Linkage isomers are coordination compounds with the same composition but different donor atoms, resulting in distinct physical and electronic structures. A pair of linkage isomers, and , derived from phenylglyoxal...
10.
Karunagala Pathiranage W, Gumataotao N, Fiedler A, Holz R, Bennett B
Biochemistry
. 2021 Nov;
60(49):3771-3782.
PMID: 34843221
A new method to trap catalytic intermediate species was employed with Fe-type nitrile hydratase from TG328-2 (NHase). NHase was incubated with substrates in a 23% (w/w) NaCl/HO eutectic system that...