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Brian A Agricola

Explore the profile of Brian A Agricola including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 37
Followers 0
Related Specialties
Hematology
Pharmacology
Molecular Biology
Top 10 Co-Authors
Robert E Donahue
Cynthia E Dunbar
Mark E Metzger
Peiman Hematti
Christof von Kalle
Ken Kuramoto
John F Tisdale
Stephanie Sellers
Aylin C Bonifacino
Stephanie E Sellers
Published In
Mol Ther
Blood
Exp Hematol
Blood Cells Mol Dis
Affiliations
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Recent Articles
1.
The presence of the carboxy-terminal fragment of fibronectin allows maintenance of non-human primate long-term hematopoietic repopulating cells during extended ex vivo culture and transduction
Sellers S, Tisdale J, Agricola B, Donahue R, Dunbar C
Exp Hematol . 2004 Apr; 32(2):163-70. PMID: 15102477
Objective: Ex vivo expansion of primitive hematopoietic cells remains of interest for gene therapy and transplantation. Previous studies reported loss of repopulating activity following culture of cells for more than...
2.
Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates
Kuramoto K, Follmann D, Hematti P, Sellers S, Agricola B, Metzger M, et al.
Blood . 2004 Feb; 103(11):4070-7. PMID: 14962906
Hematopoietic cytokines such as filgrastim are used extensively to stimulate granulocyte production or to mobilize hematopoietic progenitors into the circulation; however, their effect on more primitive hematopoietic progenitor and stem...
3.
Retrovirally transduced muscle-derived cells contribute to hematopoiesis at very low levels in the nonhuman primate model
Gao C, Kang E, Kuramoto K, Agricola B, Metzger M, von Kalle C, et al.
Mol Ther . 2003 Dec; 8(6):974-80. PMID: 14664800
Recent studies have suggested a remarkable potential of adult stem cells from a variety of organs to give rise to cells of disparate organs, but evidence of such potential at...
4.
Prolonged multilineage clonal hematopoiesis in a rhesus recipient of CD34 positive cells marked with a RD114 pseudotyped oncoretroviral vector
Kelly P, Donahue R, Vandergriff J, Takatoku M, Bonifacino A, Agricola B, et al.
Blood Cells Mol Dis . 2003 Apr; 30(1):132-43. PMID: 12667996
The ability to efficiently transfer a gene into repopulating hematopoietic stem cells would create many therapeutic opportunities. We have evaluated the ability of particles bearing an alternative envelope protein, that...
5.
Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates
Hematti P, Sellers S, Agricola B, Metzger M, Donahue R, Dunbar C
Blood . 2002 Nov; 101(6):2199-205. PMID: 12424191
Gene transfer experiments in nonhuman primates have been shown to be predictive of success in human clinical gene therapy trials. In most nonhuman primate studies, hematopoietic stem cells (HSCs) collected...
6.
Retroviral transduction and engraftment ability of primate hematopoietic progenitor and stem cells transduced under serum-free versus serum-containing conditions
Kluge K, Bonifacino A, Sellers S, Agricola B, Donahue R, Dunbar C
Mol Ther . 2002 Feb; 5(3):316-22. PMID: 11863422
The ability to efficiently transduce hematopoietic stem and progenitor cells under serum-free conditions would be desirable for safety and standardization of clinical gene therapy protocols. Using rhesus macaques, we studied...