Brett A Vaughn
Overview
Explore the profile of Brett A Vaughn including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
144
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0
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Recent Articles
11.
Ahn S, Vaughn B, Solis W, Lupher Jr M, Hallam T, Boros E
Bioconjug Chem
. 2020 Mar;
31(4):1177-1187.
PMID: 32138509
Antibody-drug conjugates (ADCs) are a class of targeted therapeutics consisting of a monoclonal antibody coupled to a cytotoxic payload. Various bioconjugation methods for producing site-specific ADCs have been reported recently,...
12.
Aluicio-Sarduy E, Thiele N, Martin K, Vaughn B, Devaraj J, Olson A, et al.
Chemistry
. 2019 Nov;
26(6):1238-1242.
PMID: 31743504
We report the first targeted nuclear medicine application of the lanthanum radionuclides La. These isotopes represent a matched pair for diagnosis via the positron emissions of La and therapy mediated...
13.
Konkankit C, Vaughn B, MacMillan S, Boros E, Wilson J
Inorg Chem
. 2019 Feb;
58(6):3895-3909.
PMID: 30793900
Combinatorial synthesis can be applied for developing a library of compounds that can be rapidly screened for biological activity. Here, we report the application of microwave-assisted combinatorial chemistry for the...
14.
Ahn S, Thach D, Vaughn B, Alford V, Preston A, Laughlin S, et al.
Mol Pharm
. 2019 Feb;
16(3):1412-1420.
PMID: 30714739
We report the nuclear and optical in vitro and in vivo imaging of SKOV-3 cells by targeting HER2 with a bimodal trastuzumab conjugate. Previously, we have shown that desferrichrome derivatives...