Angus J Koller
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Explore the profile of Angus J Koller including associated specialties, affiliations and a list of published articles.
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8
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22
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Recent Articles
1.
Blanco C, Cormier S, Koller A, Boros E, Fogg D
J Am Chem Soc
. 2025 Mar;
PMID: 40053839
The metathetical modification of biomolecules in aqueous environments holds great promise for advances at the interface of chemistry, biology, and medicine. However, rapid degradation of the metathesis catalysts necessitates their...
2.
Whetter J, Smilowicz D, Becker K, Aluicio-Sarduy E, Kelderman C, Koller A, et al.
J Am Chem Soc
. 2024 Nov;
146(48):33121-33129.
PMID: 39570707
Radioisotopes of fluorine (F), scandium (Sc, Sc), lutetium (Lu), and yttrium (Y, Y) have decay properties ideally suited for targeted nuclear imaging and therapy with small biologics, such as peptides...
3.
Koller A, Glaser O, DeLuca M, Motz R, Amason E, Carbo-Bague I, et al.
Angew Chem Int Ed Engl
. 2024 Mar;
63(18):e202319578.
PMID: 38442302
The development of inert, biocompatible chelation methods is required to harness the emerging positron emitting radionuclide Ti for radiopharmaceutical applications. Herein, we evaluate the Ti-coordination chemistry of four catechol-based, hexacoordinate...
4.
Koller A, Wang L, Deluca M, Glaser O, Robis M, Mixdorf J, et al.
Inorg Chem
. 2023 Jul;
62(50):20655-20665.
PMID: 37523384
The solution chemistry of the hydrolytic, early-transition-metal ions Ti and Sc represents a coordination chemistry challenge with important real-world implications, specifically in the context of Ti/Sc and Ti/Sc radiochemical separations....
5.
Smilowicz D, Eisenberg S, Ahn S, Koller A, Lampkin P, Boros E
Chem Sci
. 2023 May;
14(19):5038-5050.
PMID: 37206398
The efficient, large-scale synthesis of radiometallated radiopharmaceuticals represents an emerging clinical need which, to date, is inherently limited by time consuming, sequential procedures to conduct isotope separation, radiochemical labeling and...
6.
Koller A, Saini S, Chaple I, Joaqui-Joaqui M, Paterson B, Ma M, et al.
Angew Chem Int Ed Engl
. 2022 Mar;
61(22):e202201211.
PMID: 35263017
Despite its prevalence in the environment, the chemistry of the Ti ion has long been relegated to organic solutions or hydrolyzed TiO polymorphs. A knowledge gap in stabilizing molecular Ti...
7.
Whetter J, Vaughn B, Koller A, Boros E
Angew Chem Int Ed Engl
. 2021 Dec;
61(7):e202114203.
PMID: 34889014
Fluorine-18 remains the most widely clinically utilized radionuclide globally for positron emission tomography (PET). The emergence of therapeutic isotopes for the management of disease has produced a pronounced interest in...
8.
Vaughn B, Koller A, Boros E
Methods Enzymol
. 2021 Apr;
651:343-371.
PMID: 33888209
The aqueous chemistry of scandium(III) is of emerging interest for biological applications, specifically in nuclear medicine, as radioactive isotopes of scandium are becoming more readily accessible. In contrast to other...
9.
Vaughn B, Koller A, Chen Z, Ahn S, Loveless C, Cingoranelli S, et al.
Bioconjug Chem
. 2020 Dec;
32(7):1232-1241.
PMID: 33284001
The radioactive isotopes scandium-44/47 and lutetium-177 are gaining relevance for radioimaging and radiotherapy, resulting in a surge of studies on their coordination chemistry and subsequent applications. Although the trivalent ions...