Brenna J C Walsh
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Explore the profile of Brenna J C Walsh including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
125
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Recent Articles
1.
Zhang Y, Gonzalez-Gutierrez G, Legg K, Walsh B, Pis Diez C, Edmonds K, et al.
Nat Commun
. 2022 Dec;
13(1):7586.
PMID: 36481738
L-Ergothioneine (ET), the 2-thioimidazole derivative of trimethylhistidine, is biosynthesized by select fungi and bacteria, notably Mycobacterium tuberculosis, and functions as a scavenger of reactive oxygen species. The extent to which...
2.
Walsh B, Costa S, Edmonds K, Trinidad J, Issoglio F, Brito J, et al.
Antioxidants (Basel)
. 2022 Aug;
11(8).
PMID: 36009332
Hydrogen sulfide (HS) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and antibiotics. The physiological benefits often attributed to HS,...
3.
Walsh B, Giedroc D
Bio Protoc
. 2021 Jun;
11(9):e4000.
PMID: 34124301
Hydrogen sulfide (HS) is emerging as an important modulator in bacterial cytoprotection against the host immune response in infected animals, which may well be attributed to downstream highly oxidized sulfur...
4.
Capdevila D, Walsh B, Zhang Y, Dietrich C, Gonzalez-Gutierrez G, Giedroc D
Nat Chem Biol
. 2020 Oct;
17(1):65-70.
PMID: 33106663
Cysteine thiol-based transcriptional regulators orchestrate the coordinated regulation of redox homeostasis and other cellular processes by 'sensing' or detecting a specific redox-active molecule, which in turn activates the transcription of...
5.
Walsh B, Giedroc D
J Biol Chem
. 2020 Jul;
295(38):13150-13168.
PMID: 32699012
Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host efforts to cripple their viability. Major host insults are reactive oxygen and reactive nitrogen species as...
6.
Walsh B, Wang J, Edmonds K, Palmer L, Zhang Y, Trinidad J, et al.
mBio
. 2020 Jun;
11(3).
PMID: 32576676
is an opportunistic nosocomial pathogen that is the causative agent of several serious infections in humans, including pneumonia, sepsis, and wound and burn infections. is also capable of forming proteinaceous...
7.
Shen J, Walsh B, Flores-Mireles A, Peng H, Zhang Y, Zhang Y, et al.
ACS Chem Biol
. 2018 May;
13(6):1610-1620.
PMID: 29712426
Recent studies of hydrogen sulfide (HS) signaling implicate low molecular weight (LMW) thiol persulfides and other reactive sulfur species (RSS) as signaling effectors. Here, we show that a CstR protein...