Brenda J Smith
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Explore the profile of Brenda J Smith including associated specialties, affiliations and a list of published articles.
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88
Citations
1144
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Recent Articles
1.
Cook C, Lighty A, Smith B, Ford Versypt A
Front Syst Biol
. 2025 Feb;
4.
PMID: 40012834
Bone remodeling is an essential, delicately balanced physiological process of coordinated activity of bone cells that remove and deposit new bone tissue in the adult skeleton. Due to the complex...
2.
Lighty A, Islam M, Smith B, Ford Versypt A
bioRxiv
. 2025 Jan;
PMID: 39763984
Postmenopausal osteoporosis is a chronic inflammatory disease characterized by decreased bone mass and increased bone fracture risk. Estrogen deficiency during menopause plays a major role in post-menopausal osteoporosis by influencing...
3.
Dotimas L, Ojo B, Kaur A, Alake S, Dixon M, Rassi G, et al.
Nutr Res
. 2024 May;
127:13-26.
PMID: 38820937
Wheat germ (WG), a by-product of flour milling, is rich in bioactive substances that may help improve health complications associated with increased adiposity. This study investigated the effects of WG...
4.
Islam P, Ice J, Alake S, Adedigba P, Hatter B, Robinson K, et al.
JBMR Plus
. 2024 Apr;
8(5):ziae021.
PMID: 38562914
Targeting the gut-bone axis with probiotics and prebiotics is considered as a promising strategy to reduce the risk of osteoporosis. Gut-derived short chain fatty acids (SCFA) mediate the effects of...
5.
Watkins B, Smith B, Volpe S, Shen C
Nutrients
. 2024 Feb;
16(3).
PMID: 38337694
The cornerstones of good health are exercise, proper food, and sound nutrition. Physical exercise should be a lifelong routine, supported by proper food selections to satisfy nutrient requirements based on...
6.
Alake S, Ice J, Robinson K, Price P, Hatter B, Wozniak K, et al.
Physiol Rep
. 2024 Jan;
12(1):e15914.
PMID: 38217044
Characterization of the interleukin (IL)-10 knockout (KO) mouse with chronic gut inflammation, cardiovascular dysfunction, and bone loss suggests a critical role for this cytokine in interorgan communication within the gut,...
7.
Scott M, Bourgeois A, Yu Y, Burk D, Smith B, Floyd Z
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686232
Thiazolidinediones (TZD) significantly improve insulin sensitivity via action on adipocytes. Unfortunately, TZDs also degrade bone by inhibiting osteoblasts. An extract of L., termed PMI5011, improves blood glucose and insulin sensitivity...
8.
Ojo B, Alake S, Kaur A, Wong S, Keirns B, Ritchey J, et al.
Curr Dev Nutr
. 2023 May;
7(1):100023.
PMID: 37181127
Background: Commensal gut bacteria, including can produce metabolites that stimulate the release of gut antimicrobial peptides (AMPs) via the signal transducer and activator of transcription (STAT)3 pathway and prevent obesity-associated...
9.
Alake S, Lightfoot S, Wozniak K, Lin D, Chowanadisai W, Smith B, et al.
J Nutr
. 2023 Feb;
153(3):870-879.
PMID: 36813578
Background: Mice lacking IL-10 are prone to gut inflammation. Additionally, decreased production of short-chain fatty acids (SCFAs) plays a significant role in the high-fat (HF) diet-induced loss of gut epithelial...
10.
Cook C, Islam M, Smith B, Ford Versypt A
AIChE J
. 2022 Dec;
68(12).
PMID: 36567819
Bone health is determined by factors including bone metabolism or remodeling. Wnt-10b alters osteoblastogenesis through pre-osteoblast proliferation and differentiation and osteoblast apoptosis rate, which collectively lead to the increase of...