Bramanandam Manavathi
Overview
Explore the profile of Bramanandam Manavathi including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
1144
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Recent Articles
1.
Penugurti V, Dey O, Kalali S, Kashyap D, Khumukcham S, Kizhuvedath A, et al.
Cell Signal
. 2025 Jan;
128:111633.
PMID: 39884641
Pre-eclampsia is a known hypertensive disorder of pregnancy. While abnormal placentation and poor trophoblast invasion into maternal endometrium during blastocyst implantation are primary causes of pre-eclampsia, the underlying mechanisms remain...
2.
Nalla K, Chatterjee B, Poyya J, Swain A, Ghosh K, Pan A, et al.
Arch Biochem Biophys
. 2024 Nov;
763:110223.
PMID: 39581340
Purpose: Histone methyltransferases are enzymes that selectively methylate lysine or arginine residues on both histone and non-histone proteins, categorized into lysine methyltransferases and arginine methyltransferases. Notably, EZH2 and PRMT5 are...
3.
Khumukcham S, Penugurti V, Bugide S, Dwivedi A, Kumari A, Kesavan P, et al.
J Biol Chem
. 2023 Oct;
299(11):105311.
PMID: 37797694
While the role of endocytosis in focal adhesion turnover-coupled cell migration has been established in addition to its conventional role in cellular functions, the molecular regulators and precise molecular mechanisms...
4.
Padala C, Puranam K, Shyamala N, Kupsal K, Kummari R, Galimudi R, et al.
Cytokine
. 2022 Oct;
160:156024.
PMID: 36182709
Cytokines are multifunctional glycoproteins that play a vital role in the tumor microenvironment and progression of breast cancer. Genetic polymorphisms may influence the immune responses restrained by pro- and anti-inflammatory...
5.
Penugurti V, Mishra Y, Manavathi B
Biochim Biophys Acta Rev Cancer
. 2022 Aug;
1877(5):188785.
PMID: 36031088
Metabolic reprogramming is a unique but complex biochemical adaptation that allows solid tumors to tolerate various stresses that challenge cancer cells for survival. Under conditions of metabolic stress, mammalian cells...
6.
Medhi H, Khumukcham S, Manavathi B, Paik P
RSC Adv
. 2022 May;
10(40):24095-24107.
PMID: 35517325
Among the breast cancers, triple negative breast cancer (TNBC) has relatively poor outcomes with a lower survival rate and personalised chemotherapy is the only option available for treatment. Currently in...
7.
Khumukcham S, Penugurti V, Soni A, Uppala V, Hari K, Jolly M, et al.
Cancer Lett
. 2021 Nov;
526:12-28.
PMID: 34767928
While phenotypic plasticity is a critical factor contributing to tumor heterogeneity, molecular mechanisms underlying this process are largely unknown. Here we report that breast cancer cells display phenotypic diversity in...
8.
Dwivedi A, Padala C, Kumari A, Khumukcham S, Penugurti V, Ghosh S, et al.
FEBS J
. 2021 Oct;
289(6):1575-1590.
PMID: 34668648
Hematopoietic PBX-interacting protein (HPIP, also known as PBXIP1) is an estrogen receptor (ER) interacting protein that regulates estrogen-mediated breast cancer cell proliferation and tumorigenesis. However, its functional significance in the...
9.
Penugurti V, Khumukcham S, Padala C, Dwivedi A, Kamireddy K, Mukta S, et al.
Cancer Lett
. 2021 Jul;
518:243-255.
PMID: 34302919
While cancer cells rewire metabolic pathways to sustain growth and survival under metabolic stress in solid tumors, the molecular mechanisms underlying these processes remain largely unknown. In this study, cancer...
10.
Khumukcham S, Manavathi B
Biochim Biophys Acta Rev Cancer
. 2021 Jun;
1876(1):188576.
PMID: 34090932
Hematopoietic PBX interacting protein (HPIP or pre-B-cell leukemia transcription factor interacting protein (PBXIP1) was discovered two decades ago as a corepressor of pre-B-cell leukemia homeobox (PBX) 1 with a vital...