Bram Boeckx
Overview
Explore the profile of Bram Boeckx including associated specialties, affiliations and a list of published articles.
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99
Citations
5336
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Recent Articles
11.
Leduc S, Nguyen H, Richard F, Zels G, Mahdami A, De Schepper M, et al.
Clin Exp Metastasis
. 2024 Mar;
41(5):699-705.
PMID: 38548918
Metastatic breast cancer (mBC) remains incurable and liver metastases (LM) are observed in approximately 50% of all patients with mBC. In some cases, surgical resection of breast cancer liver metastases...
12.
Franken A, Bila M, Mechels A, Kint S, Van Dessel J, Pomella V, et al.
Immunity
. 2024 Mar;
57(3):541-558.e7.
PMID: 38442708
Cancer patients often receive a combination of antibodies targeting programmed death-ligand 1 (PD-L1) and cytotoxic T lymphocyte antigen-4 (CTLA4). We conducted a window-of-opportunity study in head and neck squamous cell...
13.
van Melkebeke L, Verbeek J, Bihary D, Boesch M, Boeckx B, Feio-Azevedo R, et al.
Front Immunol
. 2024 Feb;
15:1346520.
PMID: 38380322
Background And Aims: A complete understanding of disease pathophysiology in advanced liver disease is hampered by the challenges posed by clinical specimen collection. Notably, in these patients, a transjugular liver...
14.
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al.
Nat Med
. 2024 Feb;
30(5):1506.
PMID: 38332041
No abstract available.
15.
Feys S, Vanmassenhove S, Kraisin S, Yu K, Jacobs C, Boeckx B, et al.
Lancet Microbe
. 2024 Jan;
5(3):e247-e260.
PMID: 38280387
Background: COVID-19-associated pulmonary aspergillosis (CAPA) is a severe superinfection with the fungus Aspergillus affecting patients who are critically ill with COVID-19. The pathophysiology and the role of neutrophil extracellular traps...
16.
Hoes L, Voordeckers K, Dok R, Boeckx B, Steemans B, Gopaul D, et al.
iScience
. 2024 Jan;
26(12):108564.
PMID: 38213791
Although ethanol is a class I carcinogen and is linked to more than 700,000 cancer incidences, a clear understanding of the molecular mechanisms underlying ethanol-related carcinogenesis is still lacking. Further...
17.
Delafontaine S, Iannuzzo A, Bigley T, Mylemans B, Rana R, Baatsen P, et al.
J Clin Invest
. 2024 Jan;
134(4).
PMID: 38175705
Mutations in the N-terminal WD40 domain of coatomer protein complex subunit α (COPA) cause a type I interferonopathy, typically characterized by alveolar hemorrhage, arthritis, and nephritis. We described 3 heterozygous...
18.
Cappuyns S, Philips G, Vandecaveye V, Boeckx B, Schepers R, Van Brussel T, et al.
Nat Commun
. 2023 Nov;
14(1):7825.
PMID: 38030622
The combination of atezolizumab plus bevacizumab (atezo/bev) has dramatically changed the treatment landscape of advanced HCC (aHCC), achieving durable responses in some patients. Using single-cell transcriptomics, we characterize the intra-tumoural...
19.
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma
Finotto L, Cole B, Giese W, Baumann E, Claeys A, Vanmechelen M, et al.
EMBO Mol Med
. 2023 Oct;
15(11):e18144.
PMID: 37791581
Glioblastoma (GBM) remains the most malignant primary brain tumor, with a median survival rarely exceeding 2 years. Tumor heterogeneity and an immunosuppressive microenvironment are key factors contributing to the poor...
20.
Lambrechts Y, Hatse S, Richard F, Boeckx B, Floris G, Desmedt C, et al.
Cancers (Basel)
. 2023 Sep;
15(17).
PMID: 37686617
The molecular mechanisms underlying the de novo metastasis of luminal breast cancer (dnMBC) remain largely unknown. Newly diagnosed dnMBC patients (grade 2/3, ER+, PR+/-, HER2-), with available core needle biopsy...