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Braeden K Ego

Explore the profile of Braeden K Ego including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 235
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Recent Articles
1.
Rosenfeld L, LeBlanc K, Nagy A, Ego B, McCray A
Orphanet J Rare Dis . 2023 Apr; 18(1):73. PMID: 37032333
Introduction: The Undiagnosed Diseases Network (UDN), a clinical research study funded by the National Institutes of Health, aims to provide answers for patients with undiagnosed conditions and generate knowledge about...
2.
Mai E, Chan J, Goon L, Ego B, Bevers J, Wong T, et al.
J Transl Med . 2021 Dec; 19(1):517. PMID: 34930320
Background: Over the past decade, human Interleukin 33 (hIL-33) has emerged as a key contributor to the pathogenesis of numerous inflammatory diseases. Despite the existence of several commercial hIL-33 assays...
3.
Tycko J, DelRosso N, Hess G, Aradhana , Banerjee A, Mukund A, et al.
Cell . 2020 Dec; 183(7):2020-2035.e16. PMID: 33326746
Thousands of proteins localize to the nucleus; however, it remains unclear which contain transcriptional effectors. Here, we develop HT-recruit, a pooled assay where protein libraries are recruited to a reporter,...
4.
Tycko J, Wainberg M, Marinov G, Ursu O, Hess G, Ego B, et al.
Nat Commun . 2019 Sep; 10(1):4063. PMID: 31492858
Pooled CRISPR-Cas9 screens are a powerful method for functionally characterizing regulatory elements in the non-coding genome, but off-target effects in these experiments have not been systematically evaluated. Here, we investigate...
5.
Haney M, Bohlen C, Morgens D, Ousey J, Barkal A, Tsui C, et al.
Nat Genet . 2018 Nov; 50(12):1716-1727. PMID: 30397336
Phagocytosis is required for a broad range of physiological functions, from pathogen defense to tissue homeostasis, but the mechanisms required for phagocytosis of diverse substrates remain incompletely understood. Here, we...