Bradley W McIntyre
Overview
Explore the profile of Bradley W McIntyre including associated specialties, affiliations and a list of published articles.
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30
Citations
954
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Recent Articles
11.
Kim T, Billard M, Wieder E, McIntyre B, Komanduri K
Hum Immunol
. 2009 Oct;
71(1):23-8.
PMID: 19815047
The alpha(4)beta(1) integrin VLA-4 (very-late activation antigen-4) and the lineage-specific CD4 and CD8 receptors have been proposed as putative co-stimulatory receptors on T cells. To assess the relative contribution of...
12.
Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreno R, et al.
J Biol Chem
. 2009 Mar;
284(19):12645-53.
PMID: 19297325
The activation of LFA-1 (lymphocyte function-associated antigen) is a critical event for T cell co-stimulation. The mechanism of LFA-1 activation involves both affinity and avidity regulation, but the role of...
13.
Mitchell J, Brown W, Woodside D, Vanderslice P, McIntyre B
Immunol Cell Biol
. 2009 Jan;
87(4):324-36.
PMID: 19139760
Lipid rafts are small laterally mobile microdomains that are highly enriched in lymphocyte signaling molecules. GM1 gangliosides are a common lipid raft component and have been shown to be important...
14.
Billard M, McIntyre B
Immunol Cell Biol
. 2008 Jan;
86(4):381-4.
PMID: 18195724
CD45RA T cells are fully co-activated by natural beta1 integrin ligands fibronectin (FN) and VCAM-1, as well as monoclonal antibody (mAb) 19H8, which binds a combinatorial epitope of the alpha4beta1...
15.
Wang Y, Ito T, Wang Y, Homey B, Watanabe N, Martin R, et al.
Immunity
. 2006 Jun;
24(6):827-838.
PMID: 16782037
The identity of TH2 memory cells and the mechanism regulating their maintenance during allergic inflammation remain elusive. We report that circulated human CD4+ T cells expressing the prostaglandin D2 receptor...
16.
Diaz-Montero C, Wygant J, McIntyre B
Eur J Cancer
. 2006 Jun;
42(10):1491-500.
PMID: 16759849
Considerable advances in understanding the mechanisms associated with anoikis resistance of normal and malignant epithelial cells have been made. However, little is still known about the pathways involved in anoikis...
17.
Woodside D, Kram R, Mitchell J, Belsom T, Billard M, McIntyre B, et al.
J Immunol
. 2006 Apr;
176(8):5041-9.
PMID: 16585601
Cell adhesion mediated by the interaction between integrin alpha4beta1 and VCAM-1 is important in normal physiologic processes and in inflammatory and autoimmune disease. Numerous studies have mapped the alpha4beta1 binding...
18.
Qin C, Huang B, Wygant J, McIntyre B, McDonald C, Cook R, et al.
J Biol Chem
. 2006 Jan;
281(12):8034-40.
PMID: 16421105
Dentin matrix protein 1 (DMP1) is an acidic noncollagenous protein shown by gene ablations to be critical for the proper mineralization of bone and dentin. In the extracellular matrix of...
19.
Diaz-Montero C, McIntyre B
BMC Cancer
. 2005 Apr;
5:39.
PMID: 15829011
Background: Chemotherapy-induced cell death can involve the induction of apoptosis. Thus, aberrant function of the pathways involved might result in chemoresistance. Since cell adhesion to the extracellular matrix acts as...
20.
Allison J, McIntyre B, Bloch D
J Immunol
. 2005 Jan;
174(3):1144-51.
PMID: 15661866
No abstract available.