Bradley R Groveman
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Explore the profile of Bradley R Groveman including associated specialties, affiliations and a list of published articles.
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64
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Recent Articles
11.
Groveman B, Race B, Foliaki S, Williams K, Hughson A, Baune C, et al.
Acta Neuropathol Commun
. 2023 Feb;
11(1):28.
PMID: 36788566
Human cerebral organoids (COs) are three-dimensional self-organizing cultures of cerebral brain tissue differentiated from induced pluripotent stem cells. We have recently shown that COs are susceptible to infection with different...
12.
Foliaki S, Smith A, Schwarz B, Bohrnsen E, Bosio C, Williams K, et al.
PLoS Genet
. 2023 Jan;
19(1):e1010565.
PMID: 36656833
Fatal familial insomnia (FFI) is a rare neurodegenerative disease caused by a dominantly inherited single amino acid substitution (D178N) within the prion protein (PrP). No in vitro human brain tissue...
13.
Smith A, Groveman B, Winkler C, Williams K, Walters R, Yuan J, et al.
PLoS One
. 2022 Oct;
17(10):e0277051.
PMID: 36301953
Prion diseases are a group of rare, transmissible, and invariably fatal neurodegenerative diseases that affect both humans and animals. The cause of these diseases is misfolding of the prion protein...
14.
Wood A, Foliaki S, Groveman B, Walters R, Williams K, Yuan J, et al.
Sci Rep
. 2022 Sep;
12(1):15788.
PMID: 36138047
Cardiomyopathy is a co-morbidity of some prion diseases including genetic disease caused by mutations within the PrP gene (PRNP). Although the cellular prion protein (PrP) has been shown to protect...
15.
Hall S, Orru C, Serrano G, Galasko D, Hughson A, Groveman B, et al.
Acta Neuropathol Commun
. 2022 Jun;
10(1):90.
PMID: 35733234
Currently, there is a need for diagnostic markers in Lewy body disorders (LBD). α-synuclein (αSyn) RT-QuIC has emerged as a promising assay to detect misfolded αSyn in clinically or neuropathologically...
16.
Russo M, Orru C, Concha-Marambio L, Giaisi S, Groveman B, Farris C, et al.
Acta Neuropathol Commun
. 2021 Nov;
9(1):190.
PMID: 34836545
No abstract available.
17.
Russo M, Orru C, Concha-Marambio L, Giaisi S, Groveman B, Farris C, et al.
Acta Neuropathol Commun
. 2021 Nov;
9(1):179.
PMID: 34742348
Alpha-synuclein seed amplification assays (αSyn-SAAs) are promising diagnostic tools for Parkinson's disease (PD) and related synucleinopathies. They enable detection of seeding-competent alpha-synuclein aggregates in living patients and have shown high...
18.
Foliaki S, Race B, Williams K, Baune C, Groveman B, Haigh C
PLoS One
. 2021 Nov;
16(11):e0259597.
PMID: 34735539
Prion diseases are progressive, neurodegenerative diseases affecting humans and animals. Also known as the transmissible spongiform encephalopathies, for the hallmark spongiform change seen in the brain, these diseases manifest increased...
19.
Foliaki S, Schwarz B, Groveman B, Walters R, Ferreira N, Orru C, et al.
Mol Brain
. 2021 Oct;
14(1):156.
PMID: 34635127
The neuro-physiological properties of individuals with genetic pre-disposition to neurological disorders are largely unknown. Here we aimed to explore these properties using cerebral organoids (COs) derived from fibroblasts of individuals...
20.
Groveman B, Smith A, Williams K, Haigh C
PLoS Pathog
. 2021 Jul;
17(7):e1009747.
PMID: 34288977
No abstract available.