Bradley Godfrey
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Explore the profile of Bradley Godfrey including associated specialties, affiliations and a list of published articles.
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12
Citations
267
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Recent Articles
1.
Eddy S, Nair V, Hartman J, Fermin D, Eichinger F, Godfrey B, et al.
medRxiv
. 2025 Mar;
PMID: 40061330
Translational Statement: Cross-species mapping of sparsentan response in rat and human studies identified similar networks which were elevated in a subset of people with more severe focal segmental glomerulosclerosis (FSGS)...
2.
Anandakrishnan N, Yi Z, Sun Z, Liu T, Haydak J, Eddy S, et al.
medRxiv
. 2024 Apr;
PMID: 38562892
COVID-19 has been a significant public health concern for the last four years; however, little is known about the mechanisms that lead to severe COVID-associated kidney injury. In this multicenter...
3.
Lasse M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, et al.
Nat Commun
. 2023 Aug;
14(1):4903.
PMID: 37580326
Kidney organoids are a promising model to study kidney disease, but their use is constrained by limited knowledge of their functional protein expression profile. Here, we define the organoid proteome...
4.
Menon R, Otto E, Barisoni L, Ferreira R, Limonte C, Godfrey B, et al.
medRxiv
. 2023 Jul;
PMID: 37398386
Arteriolar hyalinosis in kidneys is an independent predictor of cardiovascular disease, the main cause of mortality in chronic kidney disease (CKD). The underlying molecular mechanisms of protein accumulation in the...
5.
Mariani L, Eddy S, Alakwaa F, McCown P, Harder J, Nair V, et al.
Kidney Int
. 2022 Nov;
103(3):565-579.
PMID: 36442540
The diagnosis of nephrotic syndrome relies on clinical presentation and descriptive patterns of injury on kidney biopsies, but not specific to underlying pathobiology. Consequently, there are variable rates of progression...
6.
Li H, Eksi R, Yi D, Godfrey B, Mathew L, OConnor C, et al.
PLoS Comput Biol
. 2022 Apr;
18(4):e1010040.
PMID: 35468141
Studying isoform expression at the microscopic level has always been a challenging task. A classical example is kidney, where glomerular and tubulo-interstitial compartments carry out drastically different physiological functions and...
7.
Eales J, Jiang X, Xu X, Saluja S, Akbarov A, Cano-Gamez E, et al.
Nat Genet
. 2021 May;
53(5):630-637.
PMID: 33958779
The kidney is an organ of key relevance to blood pressure (BP) regulation, hypertension and antihypertensive treatment. However, genetically mediated renal mechanisms underlying susceptibility to hypertension remain poorly understood. We...
8.
Menon R, Otto E, Sealfon R, Nair V, Wong A, Theesfeld C, et al.
Kidney Int
. 2020 Oct;
98(6):1502-1518.
PMID: 33038424
COVID-19 morbidity and mortality are increased via unknown mechanisms in patients with diabetes and kidney disease. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) for entry into host cells. Because ACE2 is...
9.
Menon R, Otto E, Sealfon R, Nair V, Wong A, Theesfeld C, et al.
medRxiv
. 2020 Jun;
PMID: 32511461
COVID-19 morbidity and mortality is increased in patients with diabetes and kidney disease via unknown mechanisms. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) for entry into host cells. Since ACE2 is...
10.
Menon R, Otto E, Hoover P, Eddy S, Mariani L, Godfrey B, et al.
JCI Insight
. 2020 Feb;
5(6).
PMID: 32107344
To define cellular mechanisms underlying kidney function and failure, the KPMP analyzes biopsy tissue in a multicenter research network to build cell-level process maps of the kidney. This study aimed...