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Bradford Powell

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Articles 9
Citations 406
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Recent Articles
1.
Pak C, Gilmore M, Bulkley J, Chakraborty P, Dagan-Rosenfeld O, Foreman A, et al.
Genet Med . 2024 May; 26(8):101164. PMID: 38757444
Purpose: The ClinGen Actionability Working Group (AWG) developed an evidence-based framework to generate actionability reports and scores of gene-condition pairs in the context of secondary findings from genome sequencing. Here...
2.
Pawliczek P, Patel R, Ashmore L, Jackson A, Bizon C, Nelson T, et al.
Hum Mutat . 2018 Oct; 39(11):1690-1701. PMID: 30311374
Effective exchange of information about genetic variants is currently hampered by the lack of readily available globally unique variant identifiers that would enable aggregation of information from different sources. The...
3.
Vora N, Powell B, Brandt A, Strande N, Hardisty E, Gilmore K, et al.
Genet Med . 2017 May; 19(11):1207-1216. PMID: 28518170
PurposeWe investigated the diagnostic and clinical performance of exome sequencing in fetuses with sonographic abnormalities with normal karyotype and microarray and, in some cases, normal gene-specific sequencing.MethodsExome sequencing was performed...
4.
Patel R, Shah N, Jackson A, Ghosh R, Pawliczek P, Paithankar S, et al.
Genome Med . 2017 Jan; 9(1):3. PMID: 28081714
Background: The success of the clinical use of sequencing based tests (from single gene to genomes) depends on the accuracy and consistency of variant interpretation. Aiming to improve the interpretation...
5.
Wolfe L, Shenk T, Powell B, Rocke T
J Wildl Dis . 2011 Nov; 47(4):888-92. PMID: 22102659
As part of an ongoing restoration program in Colorado, USA, we evaluated adverse reactions and seroconversion in captive Canada lynx (Lynx canadensis) after vaccination with a recombinant F1-V fusion protein...
6.
Rocke T, Pussini N, Smith S, Williamson J, Powell B, Osorio J
Vector Borne Zoonotic Dis . 2010 Feb; 10(1):53-8. PMID: 20158332
Baits containing recombinant raccoon poxvirus (RCN) expressing plague antigens (fraction 1 [F1] and a truncated form of the V protein-V307) were offered for voluntary consumption several times over the course...
7.
Matchett M, Biggins D, Carlson V, Powell B, Rocke T
Vector Borne Zoonotic Dis . 2010 Feb; 10(1):27-35. PMID: 20158329
Black-footed ferrets (Mustela nigripes) require extensive prairie dog colonies (Cynomys spp.) to provide habitat and prey. Epizootic plague kills both prairie dogs and ferrets and is a major factor limiting...
8.
Panchal R, Halverson K, Ribot W, Lane D, Kenny T, Abshire T, et al.
J Biol Chem . 2005 Jan; 280(11):10834-9. PMID: 15644338
Anthrax protective antigen (PA, 83 kDa), a pore-forming protein, upon protease activation to 63 kDa (PA(63)), translocates lethal factor (LF) and edema factor (EF) from endosomes into the cytosol of...
9.
Biswas B, Adhya S, Washart P, Paul B, Trostel A, Powell B, et al.
Infect Immun . 2001 Dec; 70(1):204-10. PMID: 11748184
Colonization of the gastrointestinal tract with vancomycin-resistant Enterococcus faecium (VRE) has become endemic in many hospitals and nursing homes in the United States. Such colonization predisposes the individual to VRE...