Brad A Krajina
Overview
Explore the profile of Brad A Krajina including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
177
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0
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Recent Articles
1.
LeSavage B, Zhang D, Huerta-Lopez C, Gilchrist A, Krajina B, Karlsson K, et al.
Nat Mater
. 2024 Jul;
23(8):1138-1149.
PMID: 38965405
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its fibrotic and stiff extracellular matrix. However, how the altered cell/extracellular-matrix signalling contributes to the PDAC tumour phenotype has been difficult to dissect....
2.
Yamamoto A, Huang Y, Krajina B, McBirney M, Doak A, Qu S, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(10):e2214888120.
PMID: 36853945
Necrosis in the tumor interior is a common feature of aggressive cancers that is associated with poor clinical prognosis and the development of metastasis. How the necrotic core promotes metastasis...
3.
Lee C, Hunt D, Roth J, Chiu C, Suhar R, LeSavage B, et al.
Biomaterials
. 2022 Nov;
291:121864.
PMID: 36343608
Exosome-based regenerative therapies are potentially easier to manufacture and safer to apply compared to cell-based therapies. However, many questions remain about how to bio-manufacture reproducible and potent exosomes using animal-free...
4.
Mollinger S, Krajina B, Noriega R, Salleo A, Spakowitz A
ACS Macro Lett
. 2022 May;
4(7):708-712.
PMID: 35596492
Semiconducting polymers play an important role in a wide range of optical and electronic material applications. It is widely accepted that the polymer ordering impacts charge transport in such devices....
5.
Krajina B, LeSavage B, Roth J, Zhu A, Cai P, Spakowitz A, et al.
Sci Adv
. 2021 Feb;
7(8).
PMID: 33597244
Living tissues embody a unique class of hybrid materials in which active and thermal forces are inextricably linked. Mechanical characterization of tissues demands descriptors that respect this hybrid nature. In...
6.
Cai P, Krajina B, Kratochvil M, Zou L, Zhu A, Burgener E, et al.
Soft Matter
. 2021 Jan;
17(7):1929-1939.
PMID: 33427280
We present a method for using dynamic light scattering in the single-scattering limit to measure the viscoelastic moduli of soft materials. This microrheology technique only requires a small sample volume...
7.
Cai P, Krajina B, Spakowitz A
Phys Rev E
. 2020 Sep;
102(2-1):020501.
PMID: 32942387
The viscoelastic behavior of a physically crosslinked gel involves a spectrum of molecular relaxation processes, which at the single-chain level involve the chain undergoing transient hand-to-hand motion through the network....
8.
Duarte Campos D, Lindsay C, Roth J, LeSavage B, Seymour A, Krajina B, et al.
Front Bioeng Biotechnol
. 2020 May;
8:374.
PMID: 32411691
Human tissues, both in health and disease, are exquisitely organized into complex three-dimensional architectures that inform tissue function. In biomedical research, specifically in drug discovery and personalized medicine, novel human-based...
9.
Krajina B, Zhu A, Heilshorn S, Spakowitz A
Phys Rev Lett
. 2018 Oct;
121(14):148001.
PMID: 30339454
Biological systems are equipped with a diverse repertoire of proteins that regulate DNA topology with precision that is beyond the reach of conventional polymer chemistry. Here, we harness the unique...
10.
George P, Oh B, Dewi R, Hua T, Cai L, Levinson A, et al.
Biomaterials
. 2018 Jun;
178:63-72.
PMID: 29909038
Currently, no medical therapies exist to augment stroke recovery. Stem cells are an intriguing treatment option being evaluated, but cell-based therapies have several challenges including developing a stable cell product...