Brad A Grueter
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Explore the profile of Brad A Grueter including associated specialties, affiliations and a list of published articles.
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56
Citations
1684
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Recent Articles
1.
Peeters L, Grueter B
Biol Psychiatry
. 2024 Oct;
96(9):686-688.
PMID: 39357966
No abstract available.
2.
Thibeault K, Leonard M, Kondev V, Emerson S, Bethi R, Lopez A, et al.
Biol Psychiatry
. 2024 Jun;
97(6):590-601.
PMID: 38901723
Background: Substance use disorder is characterized by long-lasting changes in reward-related brain regions, such as the nucleus accumbens. Previous work has shown that cocaine exposure induces plasticity in broad, genetically...
3.
Zachry J, Kutlu M, Yoon H, Leonard M, Chevee M, Patel D, et al.
Neuron
. 2023 Dec;
112(5):835-849.e7.
PMID: 38134921
At the core of value-based learning is the nucleus accumbens (NAc). D1- and D2-receptor-containing medium spiny neurons (MSNs) in the NAc core are hypothesized to have opposing valence-based roles in...
4.
Kondev V, Najeed M, Yasmin F, Morgan A, Loomba N, Johnson K, et al.
Cell Rep
. 2023 Sep;
42(9):113027.
PMID: 37703881
The endocannabinoid (eCB) system is a key modulator of glutamate release within limbic neurocircuitry and thus heavily modulates stress responsivity and adaptation. The ventral hippocampus (vHPC)-basolateral amygdala (BLA) circuit has...
5.
Kondev V, Najeed M, Loomba N, Brown J, Winder D, Grueter B, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(34):e2300585120.
PMID: 37590414
Interneuron populations within the nucleus accumbens (NAc) orchestrate excitatory-inhibitory balance, undergo experience-dependent plasticity, and gate-motivated behavior, all biobehavioral processes heavily modulated by endogenous cannabinoid (eCB) signaling. While eCBs are well...
6.
Manz K, Zepeda J, Zurawski Z, Hamm H, Grueter B
Front Cell Neurosci
. 2023 May;
17:1165261.
PMID: 37206665
The nucleus accumbens (NAc) guides reward-related motivated behavior implicated in pathological behavioral states, including addiction and depression. These behaviors depend on the precise neuromodulatory actions of G-coupled G-protein-coupled receptors (GPCRs)...
7.
Winters N, Yasmin F, Kondev V, Grueter B, Patel S
ACS Chem Neurosci
. 2023 May;
14(11):2008-2015.
PMID: 37163725
Cannabidiol (CBD) is a non-psychoactive constituent of the plant that has purported effectiveness in treating an array of stress-related neuropsychiatric disorders. The amygdala is a subcortical brain structure that regulates...
8.
Winters N, Kondev V, Loomba N, Delpire E, Grueter B, Patel S
Cell Rep
. 2023 Feb;
42(3):112159.
PMID: 36842084
The lateral habenula (LHb) encodes aversive states, and its dysregulation is implicated in neuropsychiatric disorders, including depression. The endocannabinoid (eCB) system is a neuromodulatory signaling system that broadly serves to...
9.
Jameson A, Siemann J, Melchior J, Calipari E, McMahon D, Grueter B
eNeuro
. 2023 Feb;
10(2).
PMID: 36781229
Circadian photoperiod, or day length, changes with the seasons and influences behavior to allow animals to adapt to their environment. Photoperiod is also associated with seasonal rhythms of affective state,...
10.
Kondev V, Bluett R, Najeed M, Rosas-Vidal L, Grueter B, Patel S
Neurobiol Stress
. 2023 Jan;
22:100510.
PMID: 36594052
The endogenous cannabinoid, 2-arachidonoylglycerol (2-AG), plays a key role in the regulation of anxiety- and stress-related behavioral phenotypes and may represent a novel target for the treatment of anxiety disorders....