Boy Helder
Overview
Explore the profile of Boy Helder including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
11
Citations
268
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0
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Recent Articles
1.
Merino-Vico A, van Hamburg J, Tuijnenburg P, Frazzei G, Al-Soudi A, Bonasia C, et al.
J Autoimmun
. 2023 Nov;
142:103133.
PMID: 37931331
B lineage cells are critically involved in ANCA-associated vasculitis (AAV), evidenced by alterations in circulating B cell subsets and beneficial clinical effects of rituximab (anti-CD20) therapy. This treatment renders a...
2.
Kaaij M, Helder B, van Mens L, van de Sande M, Baeten D, Tas S
Sci Rep
. 2020 Dec;
10(1):21094.
PMID: 33273664
Spondyloarthritis (SpA) is characterized by inflammation and new bone formation. The exact pathophysiology underlying these processes remains elusive. We propose that the extensive neoangiogenesis in SpA could play a role...
3.
Ramos M, Garcia S, Helder B, Aarrass S, Reedquist K, Jacobsen S, et al.
J Transl Autoimmun
. 2020 Oct;
3:100066.
PMID: 33015599
Rheumatoid arthritis (RA) is chronic autoimmune disease which etiology remains unknown. Several cell types have been described to potentiate/aggravate the arthritic process however the initiating event in synovial inflammation is...
4.
van der Poel M, Ulas T, Mizee M, Hsiao C, Miedema S, Adelia , et al.
Nat Commun
. 2019 Mar;
10(1):1139.
PMID: 30867424
Here we report the transcriptional profile of human microglia, isolated from normal-appearing grey matter (GM) and white matter (WM) of multiple sclerosis (MS) and non-neurological control donors, to find possible...
5.
Maracle C, Jeucken K, Helder B, van Gulik T, Steins A, van Laarhoven H, et al.
Oncotarget
. 2018 Jul;
9(47):28445-28455.
PMID: 29983872
Angiogenesis is essential for colorectal cancer (CRC) progression, as demonstrated by the beneficial clinical effects of therapeutics inhibiting VEGF signaling. However, alternative mechanisms of neovascularization can develop, resulting in treatment...
6.
Maracle C, Agca R, Helder B, Meeuwsen J, Niessen H, Biessen E, et al.
Atherosclerosis
. 2018 Feb;
270:33-41.
PMID: 29407886
Background And Aims: Neovascularization is associated with atherosclerotic plaque instability and increased chance of myocardial infarction (MI). Patients with chronic inflammatory diseases (CID) have increased risk of atherosclerosis, and evidence...
7.
Maracle C, Kucharzewska P, Helder B, van der Horst C, Correa de Sampaio P, Noort A, et al.
Rheumatology (Oxford)
. 2016 Nov;
56(2):294-302.
PMID: 27864565
Objective: Angiogenesis is crucial in RA disease progression. Lymphotoxin β receptor (LTβR)-induced activation of the non-canonical nuclear factor-κB (NF-κB) pathway via NF-κB-inducing kinase (NIK) has been implicated in this process....
8.
Lebre M, Vieira P, Tang M, Aarrass S, Helder B, Newsom-Davis T, et al.
J Leukoc Biol
. 2016 Oct;
101(3):775-783.
PMID: 27733582
Bone and cartilage destruction is one of the key manifestations of rheumatoid arthritis (RA). Although the role of T helper (Th)17 cells in these processes is clear, the role of...
9.
Ramos M, Teunissen M, Helder B, Aarrass S, de Hair M, van Kuijk A, et al.
Rheumatology (Oxford)
. 2016 May;
55(9):1575-84.
PMID: 27179104
Objectives: We aimed to investigate the early changes in expression of C-type lectin domain family 9, member A (CLEC9A), a C-type lectin that is specifically expressed by the CD141(+) dendritic...
10.
Noort A, van Zoest K, van Baarsen L, Maracle C, Helder B, Papazian N, et al.
Am J Pathol
. 2015 May;
185(7):1935-43.
PMID: 25963989
Tertiary lymphoid structures (TLSs) in chronic inflammation, including rheumatoid arthritis (RA) synovial tissue (ST), often contain high endothelial venules and follicular dendritic cells (FDCs). Endothelial cell (EC)-specific lymphotoxin β (LTβ)...