Borja Ocon
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Explore the profile of Borja Ocon including associated specialties, affiliations and a list of published articles.
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21
Citations
707
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Recent Articles
1.
Ocon B, Xiang M, Bi Y, Tan S, Brulois K, Ayesha A, et al.
Nature
. 2024 Sep;
635(8039):736-745.
PMID: 39293486
Tissue-selective chemoattractants direct lymphocytes to epithelial surfaces to establish local immune environments, regulate immune responses to food antigens and commensal organisms, and protect from pathogens. Homeostatic chemoattractants for small intestines,...
2.
Hernandez-Chirlaque C, Aranda C, Ocon B, Polo J, Martinez-Augustin O, Sanchez de Medina F
Animals (Basel)
. 2021 Apr;
11(3).
PMID: 33805697
Serum protein concentrates have been shown to exert in vivo anti-inflammatory effects. Specific effects on different cell types and their mechanism of action remain unraveled. We aimed to characterize the...
3.
Arredondo-Amador M, Aranda C, Ocon B, Gonzalez R, Martinez-Augustin O, Sanchez de Medina F
Br J Pharmacol
. 2021 Mar;
178(12):2482-2495.
PMID: 33684964
Background And Purpose: Glucocorticoids are the first line treatment for the flare-ups of inflammatory bowel disease, but they have significant limitations. The objective of this study is to investigate whether...
4.
Ballet R, Brennan M, Brandl C, Feng N, Berri J, Cheng J, et al.
Nat Immunol
. 2021 Feb;
22(3):381-390.
PMID: 33589816
The integrin αβ selectively regulates lymphocyte trafficking and adhesion in the gut and gut-associated lymphoid tissue (GALT). Here, we describe unexpected involvement of the tyrosine phosphatase Shp1 and the B...
5.
Aranda C, Arredondo-Amador M, Ocon B, Lavin J, Aransay A, Martinez-Augustin O, et al.
FASEB J
. 2019 Oct;
33(12):14067-14082.
PMID: 31657630
Glucocorticoids (GCs) are important hormones involved in the regulation of multiple physiologic functions. GCs are also widely used in anti-inflammatory/immunosuppressant drugs. GCs are synthesized by the adrenal cortex as part...
6.
Rivero-Gutierrez B, Aranda C, Ocon B, Arredondo M, Martinez-Augustin O, Sanchez de Medina F
Pharmacol Res
. 2019 Jul;
147:104356.
PMID: 31356864
Besides its function controlling energy expenditure and food intake, leptin is an important modulator of inflammatory responses. The role of leptin in intestinal inflammation remains controversial, since both pro-inflammatory and...
7.
Anzola A, Gonzalez R, Gamez-Belmonte R, Ocon B, Aranda C, Martinez-Moya P, et al.
Sci Rep
. 2018 Nov;
8(1):17350.
PMID: 30478292
Regulation of miR-146a abundance and its role in intestinal inflammation and particularly in intestinal epithelial cells (IECs) has been poorly studied. Here we study the relationship between bacterial antigens and...
8.
Romero-Calvo I, Ocon B, Gamez-Belmonte R, Hernandez-Chirlaque C, De Jonge H, Bijvelds M, et al.
Pflugers Arch
. 2018 Aug;
470(11):1705-1717.
PMID: 30094477
One of the cardinal symptoms of intestinal inflammation is diarrhea. Acute intestinal inflammation is associated with inhibition of ion absorption and increased secretion, along with fluid leakage due to epithelial...
9.
Aranda C, Ocon B, Arredondo-Amador M, Suarez M, Zarzuelo A, Chazin W, et al.
Br J Pharmacol
. 2018 Jul;
175(19):3797-3812.
PMID: 30007036
Background And Purpose: Calprotectin is a heterodimer composed of two myeloid-related proteins, S100A8 and S100A9, that is abundant in neutrophils and monocytes/macrophages. Faecal levels of calprotectin are used routinely to...
10.
Al-Aqil F, Monte M, Peleteiro-Vigil A, Briz O, Rosales R, Gonzalez R, et al.
Biochim Biophys Acta Mol Basis Dis
. 2018 Jun;
1864(9 Pt B):2927-2937.
PMID: 29883717
At high doses, glucocorticoids (GC) have been associated with enhanced serum bile acids and liver injury. We have evaluated the effect of GC, in the absence of hepatotoxicity, on FXR/FGF91(Fgf15)/FGF21-mediated...