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Boguslawa Sadowski

Explore the profile of Boguslawa Sadowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 450
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Recent Articles
1.
Meschkat M, Steyer A, Weil M, Kusch K, Jahn O, Piepkorn L, et al.
Nat Commun . 2022 Mar; 13(1):1163. PMID: 35246535
Myelin, the electrically insulating sheath on axons, undergoes dynamic changes over time. However, it is composed of proteins with long lifetimes. This raises the question how such a stable structure...
2.
Moyon S, Frawley R, Marechal D, Huang D, Marshall-Phelps K, Kegel L, et al.
Nat Commun . 2021 Jun; 12(1):3359. PMID: 34099715
The mechanisms regulating myelin repair in the adult central nervous system (CNS) are unclear. Here, we identify DNA hydroxymethylation, catalyzed by the Ten-Eleven-Translocation (TET) enzyme TET1, as necessary for myelin...
3.
Stuendl A, Kraus T, Chatterjee M, Zapke B, Sadowski B, Moebius W, et al.
Mov Disord . 2021 May; 36(11):2508-2518. PMID: 34002893
Background: Extracellular vesicles are small vesicles that are released from many cells, including neurons. α-Synuclein has recently been described in extracellular vesicles derived from the central nervous system and may...
4.
Weil M, Ruhwedel T, Meschkat M, Sadowski B, Mobius W
Methods Mol Biol . 2019 Mar; 1936:343-375. PMID: 30820909
In this chapter, we describe protocols to study different aspects of oligodendrocytes and myelin using electron microscopy. First, we describe in detail how to prepare central nervous system tissue routinely...
5.
Schirmer L, Mobius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, et al.
Elife . 2018 Sep; 7. PMID: 30204081
Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of which encodes the inward-rectifying potassium channel KIR4.1, causes...
6.
Tarasenko D, Barbot M, Jans D, Kroppen B, Sadowski B, Heim G, et al.
J Cell Biol . 2017 Mar; 216(4):889-899. PMID: 28254827
The inner membrane (IM) of mitochondria displays an intricate, highly folded architecture and can be divided into two domains: the inner boundary membrane adjacent to the outer membrane and invaginations...
7.
Schminke B, Muhammad H, Bode C, Sadowski B, Gerter R, Gersdorff N, et al.
Cell Mol Life Sci . 2013 Aug; 71(6):1081-96. PMID: 23912900
Discoidin domain receptor 1 (DDR-1)-deficient mice exhibited a high incidence of osteoarthritis (OA) in the temporomandibular joint (TMJ) as early as 9 weeks of age. They showed typical histological signs...
8.
Koelling S, Kruegel J, Irmer M, Path J, Sadowski B, Miro X, et al.
Cell Stem Cell . 2009 Apr; 4(4):324-35. PMID: 19341622
The regeneration of diseased hyaline cartilage continues to be a great challenge, mainly because degeneration--caused either by major injury or by age-related processes--can overextend the tissue's self-renewal capacity. We show...
9.
Kruegel J, Sadowski B, Miosge N
Arthritis Rheum . 2008 Apr; 58(5):1422-32. PMID: 18438862
Objective: To investigate the presence and function of nidogen-1 and nidogen-2 in healthy human cartilage and in late-stage osteoarthritis (OA) cartilage. Methods: The location and quantity of nidogen-1 and nidogen-2...