Bob Strome
Overview
Explore the profile of Bob Strome including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
337
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hsu I, Strome B, Lash E, Robbins N, Cowen L, Moses A
PLoS Genet
. 2021 Sep;
17(9):e1009629.
PMID: 34506483
Stochastic signaling dynamics expand living cells' information processing capabilities. An increasing number of studies report that regulators encode information in their pulsatile dynamics. The evolutionary mechanisms that lead to complex...
2.
Zarin T, Strome B, Peng G, Pritisanac I, Forman-Kay J, Moses A
Elife
. 2021 Feb;
10.
PMID: 33616531
In previous work, we showed that intrinsically disordered regions (IDRs) of proteins contain sequence-distributed molecular features that are conserved over evolution, despite little sequence similarity that can be detected in...
3.
Zarin T, Strome B, Nguyen Ba A, Alberti S, Forman-Kay J, Moses A
Elife
. 2019 Jul;
8.
PMID: 31264965
Intrinsically disordered regions make up a large part of the proteome, but the sequence-to-function relationship in these regions is poorly understood, in part because the primary amino acid sequences of...
4.
Hsu I, Strome B, Plotnikov S, Moses A
G3 (Bethesda)
. 2018 Dec;
9(2):561-570.
PMID: 30573469
Several examples of transcription factors that show stochastic, unsynchronized pulses of nuclear localization have been described. Here we show that under constant calcium stress, nuclear localization pulses of the transcription...
5.
Strome B, Hsu I, Li Cheong Man M, Zarin T, Nguyen Ba A, Moses A
BMC Syst Biol
. 2018 Jul;
12(1):75.
PMID: 29970070
Background: The effort to characterize intrinsically disordered regions of signaling proteins is rapidly expanding. An important class of disordered interaction modules are ubiquitous and functionally diverse elements known as short...
6.
Lu A, Chong Y, Hsu I, Strome B, Handfield L, Kraus O, et al.
Elife
. 2018 Apr;
7.
PMID: 29620521
The evaluation of protein localization changes on a systematic level is a powerful tool for understanding how cells respond to environmental, chemical, or genetic perturbations. To date, work in understanding...
7.
Nguyen Ba A, Strome B, Osman S, Legere E, Zarin T, Moses A
PLoS Genet
. 2017 Apr;
13(4):e1006735.
PMID: 28410373
Regulatory networks often increase in complexity during evolution through gene duplication and divergence of component proteins. Two models that explain this increase in complexity are: 1) adaptive changes after gene...
8.
Nguyen Ba A, Strome B, Hua J, Desmond J, Gagnon-Arsenault I, Weiss E, et al.
PLoS Comput Biol
. 2014 Dec;
10(12):e1003977.
PMID: 25474245
Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization. Consistent with functional divergence after gene duplication, recent studies have...
9.
Handfield L, Strome B, Chong Y, Moses A
Bioinformatics
. 2014 Nov;
31(6):940-7.
PMID: 25398614
Motivation: Quantifying variability in protein expression is a major goal of systems biology and cell-to-cell variability in subcellular localization pattern has not been systematically quantified. Results: We define a local...
10.
Mays C, Coomaraswamy J, Watts J, Yang J, Ko K, Strome B, et al.
FEBS J
. 2013 Nov;
281(3):862-76.
PMID: 24286250
Cellular prion protein (PrP(C)) misfolds to form infectivity-associated scrapie prion protein and generates C-terminal fragments C1 and C2 in healthy and prion-infected animals. C1 cleavage occurs N-terminally of PrP(C)'s hydrophobic...