Blake B Rasmussen
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Explore the profile of Blake B Rasmussen including associated specialties, affiliations and a list of published articles.
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111
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8552
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Recent Articles
1.
Kureel S, Maroto R, Aniqua M, Powell S, Singh E, Margadant F, et al.
Aging Cell
. 2025 Mar;
:e70008.
PMID: 40033886
The presence of senescent cells causes age-related pathologies since their removal by genetic or pharmacological means, as well as possibly by exercise, improves outcomes in animal models. An alternative to...
2.
Von Ruff Z, Miller M, Moro T, Reidy P, Ebert S, Volpi E, et al.
Geroscience
. 2025 Feb;
PMID: 40011348
Sarcopenia increases the risk of frailty, morbidity, and mortality in older adults. Resistance exercise training improves muscle size and function; however, the response to exercise training is variable in older...
3.
Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, et al.
Sci Adv
. 2024 May;
10(20):eadj5942.
PMID: 38758779
Acetyl-CoA synthetase short-chain family member 1 (ACSS1) uses acetate to generate mitochondrial acetyl-CoA and is regulated by deacetylation by sirtuin 3. We generated an ACSS1-acetylation (Ac) mimic mouse, where lysine-635...
4.
Jakicic J, Kohrt W, Houmard J, Miller M, Radom-Aizik S, Rasmussen B, et al.
J Appl Physiol (1985)
. 2024 Apr;
137(3):473-493.
PMID: 38634503
Physical activity, including structured exercise, is associated with favorable health-related chronic disease outcomes. Although there is evidence of various molecular pathways that affect these responses, a comprehensive molecular map of...
5.
Ebert S, Nicolas C, Schreiber P, Lopez J, Taylor A, Judge A, et al.
Animals (Basel)
. 2024 Jan;
14(2).
PMID: 38254356
Muscle atrophy and weakness are prevalent and debilitating conditions in dogs that cannot be reliably prevented or treated by current approaches. In non-canine species, the natural dietary compound ursolic acid...
6.
Maroto R, Graber T, Romsdahl T, Kudlicki A, Russell W, Rasmussen B
J Nutr
. 2023 Oct;
153(12):3397-3405.
PMID: 37898335
Background: Regulation of mechanistic target of rapamycin complex 1 (mTORC1) plays an important role in aging and nutrition. For example, caloric restriction reduces mTORC1 signaling and extends lifespan, whereas nutrient...
7.
Graber T, Maroto R, Thompson J, Widen S, Man Z, Pajski M, et al.
J Ageing Longev
. 2023 Oct;
3(2):159-178.
PMID: 37876943
One inevitable consequence of aging is the gradual deterioration of physical function and exercise capacity, driven in part by the adverse effect of age on muscle tissue. We hypothesized that...
8.
Marcotte G, Miller M, Kunz H, Ryan Z, Strub M, Vanderboom P, et al.
JCI Insight
. 2023 Oct;
8(22).
PMID: 37815864
Aging and many illnesses and injuries impair skeletal muscle mass and function, but the molecular mechanisms are not well understood. To better understand the mechanisms, we generated and studied transgenic...
9.
Reidy P, Borack M, Dickinson J, Carroll C, Burd N, Drummond M, et al.
Am J Physiol Endocrinol Metab
. 2023 Jun;
325(2):E113-E118.
PMID: 37315157
Several factors affect muscle protein synthesis (MPS) in the postabsorptive state. Extreme physical inactivity (e.g., bedrest) may reduce basal MPS, whereas walking may augment basal MPS. We hypothesized that outpatients...
10.
Miller M, Marcotte G, Basisty N, Wehrfritz C, Ryan Z, Strub M, et al.
Geroscience
. 2023 Apr;
45(4):2525-2543.
PMID: 37014538
Aging slowly erodes skeletal muscle strength and mass, eventually leading to profound functional deficits and muscle atrophy. The molecular mechanisms of skeletal muscle aging are not well understood. To better...