Birthe Trautz
Overview
Explore the profile of Birthe Trautz including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
129
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0
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Recent Articles
1.
Trautz B, Wiedemann H, Luchtenborg C, Pierini V, Kranich J, Glass B, et al.
J Biol Chem
. 2019 Dec;
294(49):18951.
PMID: 31811051
No abstract available.
2.
Ananth S, Morath K, Trautz B, Tibroni N, Shytaj I, Obermaier B, et al.
J Virol
. 2019 Oct;
94(1).
PMID: 31597760
HIV-1 Nef promotes virus spread and disease progression by altering host cell transport and signaling processes through interaction with multiple host cell proteins. The N-terminal region in HIV-1 Nef encompassing...
3.
Lamas-Murua M, Stolp B, Kaw S, Thoma J, Tsopoulidis N, Trautz B, et al.
J Immunol
. 2018 Sep;
201(9):2731-2743.
PMID: 30257886
HIV-1 Nef is a multifunctional protein that optimizes virus spread and promotes immune evasion of infected cells to accelerate disease progression in AIDS patients. As one of its activities, Nef...
4.
Kmiec D, Akbil B, Ananth S, Hotter D, Sparrer K, Sturzel C, et al.
PLoS Pathog
. 2018 Aug;
14(8):e1007269.
PMID: 30125328
SERINC5 is a host restriction factor that impairs infectivity of HIV-1 and other primate lentiviruses and is counteracted by the viral accessory protein Nef. However, the importance of SERINC5 antagonism...
5.
Trautz B, Wiedemann H, Luchtenborg C, Pierini V, Kranich J, Glass B, et al.
J Biol Chem
. 2017 Jun;
292(33):13702-13713.
PMID: 28659343
The host-cell restriction factor SERINC5 potently suppresses the infectivity of HIV, type 1 (HIV-1) particles, and is counteracted by the viral pathogenesis factor Nef. However, the molecular mechanism by which...
6.
Trautz B, Pierini V, Wombacher R, Stolp B, Chase A, Pizzato M, et al.
J Virol
. 2016 Sep;
90(23):10915-10927.
PMID: 27681140
Importance: HIV-1 Nef critically determines virus spread and disease progression in infected individuals by incompletely defined mechanisms. SERINC3 and SERINC5 were recently identified as potent inhibitors of HIV particle infectivity...