Birgit Schutz
Overview
Explore the profile of Birgit Schutz including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
496
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Recent Articles
1.
Katholnig K, Schutz B, Fritsch S, Schorghofer D, Linke M, Sukhbaatar N, et al.
JCI Insight
. 2019 Oct;
4(20).
PMID: 31619583
The mechanistic target of rapamycin complex 2 (mTORC2) is a potentially novel and promising anticancer target due to its critical roles in proliferation, apoptosis, and metabolic reprogramming of cancer cells....
2.
Vondra S, Kunihs V, Eberhart T, Eigner K, Bauer R, Haslinger P, et al.
J Lipid Res
. 2019 Sep;
60(11):1922-1934.
PMID: 31530576
During pregnancy, extravillous trophoblasts (EVTs) invade the maternal decidua and remodel the local vasculature to establish blood supply for the growing fetus. Compromised EVT function has been linked to aberrant...
3.
Kinslechner K, Schutz B, Pistek M, Rapolter P, Weitzenbock H, Hundsberger H, et al.
Int J Mol Sci
. 2019 Mar;
20(5).
PMID: 30823658
Melanoma is a skin tumor with a high tendency for metastasis and thus is one of the deadliest cancers worldwide. Here, we investigated the expression of the scavenger receptor class...
4.
Velicky P, Meinhardt G, Plessl K, Vondra S, Weiss T, Haslinger P, et al.
PLoS Genet
. 2018 Oct;
14(10):e1007698.
PMID: 30312291
Genome amplification and cellular senescence are commonly associated with pathological processes. While physiological roles for polyploidization and senescence have been described in mouse development, controversy exists over their significance in...
5.
Eigner K, Filik Y, Mark F, Schutz B, Klambauer G, Moriggl R, et al.
Sci Rep
. 2017 Dec;
7(1):17498.
PMID: 29235576
The mechanisms hallmarking melanoma progression are insufficiently understood. Here we studied the impact of the unfolded protein response (UPR) - a signalling cascade playing ambiguous roles in carcinogenesis - in...
6.
Kinslechner K, Schorghofer D, Schutz B, Vallianou M, Wingelhofer B, Mikulits W, et al.
Mol Cancer Res
. 2017 Oct;
16(1):135-146.
PMID: 28974560
Metastatic melanoma is hallmarked by elevated glycolytic flux and alterations in cholesterol homeostasis. The contribution of cholesterol transporting receptors for the maintenance of a migratory and invasive phenotype is not...
7.
Linke M, Pham H, Katholnig K, Schnoller T, Miller A, Demel F, et al.
Nat Immunol
. 2017 Jan;
18(3):293-302.
PMID: 28092373
The aggregation of hypertrophic macrophages constitutes the basis of all granulomatous diseases, such as tuberculosis or sarcoidosis, and is decisive for disease pathogenesis. However, macrophage-intrinsic pathways driving granuloma initiation and...
8.
Schutz B, Koppensteiner A, Schorghofer D, Kinslechner K, Timelthaler G, Eferl R, et al.
Sci Rep
. 2016 Nov;
6:37253.
PMID: 27853253
Melanoma is the most aggressive type of skin cancer and one of the most frequent tumours in young adults. Identification of primary tumours prone to develop metastasis is of paramount...
9.
Preitschopf A, Schorghofer D, Kinslechner K, Schutz B, Zwickl H, Rosner M, et al.
Stem Cells Transl Med
. 2016 Mar;
5(5):580-90.
PMID: 27025692
Unlabelled: Amniotic fluid stem (AFS) cells represent a major source of donor cells for cartilage repair. Recently, it became clear that mammalian target of rapamycin (mTOR) inhibition has beneficial effects...
10.
Schorghofer D, Kinslechner K, Preitschopf A, Schutz B, Rohrl C, Hengstschlager M, et al.
Reprod Biol Endocrinol
. 2015 Aug;
13:88.
PMID: 26251134
Background: Human prostate cancer represents one of the most frequently diagnosed cancers in men worldwide. Currently, diagnostic methods are insufficient to identify patients at risk for aggressive prostate cancer, which...