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» Authors » Birgit Kagerbauer

Birgit Kagerbauer

Explore the profile of Birgit Kagerbauer including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 820
Followers 0
Related Specialties
Genetics
Molecular Biology
General Medicine
Top 10 Co-Authors
Xavier Estivill
Eulalia Marti
Yolanda Espinosa-Parrilla
Monica Banez-Coronel
Monica Gratacos
Georgia Escaramis
Isidre Ferrer
Silvia Porta
Monica Guidi
Margarita Muinos-Gimeno
Published In
Hum Mol Genet
Immunogenetics
BMC Mol Biol
RNA Biol
Hum Mutat
Affiliations
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Recent Articles
1.
Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels
Rue L, Banez-Coronel M, Creus-Muncunill J, Giralt A, Alcala-Vida R, Mentxaka G, et al.
J Clin Invest . 2016 Oct; 126(11):4319-4330. PMID: 27721240
Huntington's disease (HD) is a polyglutamine disorder caused by a CAG expansion in the Huntingtin (HTT) gene exon 1. This expansion encodes a mutant protein whose abnormal function is traditionally...
2.
Evidence for the biogenesis of more than 1,000 novel human microRNAs
Friedlander M, Lizano E, Houben A, Bezdan D, Banez-Coronel M, Kudla G, et al.
Genome Biol . 2014 Apr; 15(4):R57. PMID: 24708865
Background: MicroRNAs (miRNAs) are established regulators of development, cell identity and disease. Although nearly two thousand human miRNA genes are known and new ones are continuously discovered, no attempt has...
3.
Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction
Minones-Moyano E, Friedlander M, Pallares J, Kagerbauer B, Porta S, Escaramis G, et al.
RNA Biol . 2013 May; 10(7):1093-106. PMID: 23673382
MicroRNAs (miRNAs) and other small non-coding RNAs (sncRNAs) are post-transcriptional regulators of gene expression, playing key roles in neuronal development, plasticity, and disease. Transcriptome deregulation caused by miRNA dysfunction has...
4.
A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity
Banez-Coronel M, Porta S, Kagerbauer B, Mateu-Huertas E, Pantano L, Ferrer I, et al.
PLoS Genet . 2012 Mar; 8(2):e1002481. PMID: 22383888
Huntington's disease (HD) is an autosomal dominantly inherited disorder caused by the expansion of CAG repeats in the Huntingtin (HTT) gene. The abnormally extended polyglutamine in the HTT protein encoded...
5.
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
Minones-Moyano E, Porta S, Escaramis G, Rabionet R, Iraola S, Kagerbauer B, et al.
Hum Mol Genet . 2011 May; 20(15):3067-78. PMID: 21558425
MicroRNAs (miRNAs) are post-transcriptional gene expression regulators, playing key roles in neuronal development, plasticity and disease. Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by the presence...
6.
Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways
Muinos-Gimeno M, Espinosa-Parrilla Y, Guidi M, Kagerbauer B, Sipila T, Maron E, et al.
Biol Psychiatry . 2010 Dec; 69(6):526-33. PMID: 21168126
Background: The involvement of microRNAs (miRNAs) in neuronal differentiation and synaptic plasticity suggests a role for miRNAs in psychiatric disorders; association analyses and functional approaches were used to evaluate the...
7.
Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells
Guidi M, Muinos-Gimeno M, Kagerbauer B, Marti E, Estivill X, Espinosa-Parrilla Y
BMC Mol Biol . 2010 Dec; 11:95. PMID: 21143953
Background: Neurotrophins and their receptors are key molecules in the regulation of neuronal differentiation and survival. They mediate the survival of neurons during development and adulthood and are implicated in...
8.
Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia
Saus E, Soria V, Escaramis G, Vivarelli F, Crespo J, Kagerbauer B, et al.
Hum Mol Genet . 2010 Jul; 19(20):4017-25. PMID: 20656788
Previous studies in mice have reported five different microRNAs (miRNAs; miR-219-1/132/183/96/182) to be modulators of the endogenous circadian clock and have presented experimental evidence for some of the genes involved...
9.
Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders
Muinos-Gimeno M, Guidi M, Kagerbauer B, Martin-Santos R, Navines R, Alonso P, et al.
Hum Mutat . 2009 Apr; 30(7):1062-71. PMID: 19370765
Genetic and functional data indicate that variation in the expression of the neurotrophin-3 receptor gene (NTRK3) may have an impact on neuronal plasticity, suggesting a role for NTRK3 in the...
10.
Differential methylation pattern of the X-linked lymphoproliferative (XLP) disease gene SH2D1A correlates with the cell lineage-specific transcription
Parolini O, Weinhausel A, Kagerbauer B, Sassmann J, Holter W, Gadner H, et al.
Immunogenetics . 2003 Apr; 55(2):116-21. PMID: 12709835
SH2D1A, the X-linked lymphoproliferative disease (XLP) gene, encodes a cytoplasmic protein that plays an essential role in controlling Epstein-Barr virus infection. It is expressed in T and NK cells, but...