Bingcan Liu
Overview
Explore the profile of Bingcan Liu including associated specialties, affiliations and a list of published articles.
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10
Citations
306
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Recent Articles
1.
Szychowski J, Papp R, Dietrich E, Liu B, Vallee F, Leclaire M, et al.
J Med Chem
. 2022 Jul;
65(15):10251-10284.
PMID: 35880755
PKMYT1 is a regulator of CDK1 phosphorylation and is a compelling therapeutic target for the treatment of certain types of DNA damage response cancers due to its established synthetic lethal...
2.
Gallo D, Young J, Fourtounis J, Martino G, Alvarez-Quilon A, Bernier C, et al.
Nature
. 2022 Apr;
604(7907):749-756.
PMID: 35444283
Amplification of the CCNE1 locus on chromosome 19q12 is prevalent in multiple tumour types, particularly in high-grade serous ovarian cancer, uterine tumours and gastro-oesophageal cancers, where high cyclin E levels...
3.
Henderson J, Bilimoria D, Bubenik M, Cadilhac C, Cottrell K, Dietrich E, et al.
Bioorg Med Chem Lett
. 2015 Jan;
25(4):944-7.
PMID: 25577041
The treatment of HCV with highly efficacious, well-tolerated, interferon-free regimens is a compelling clinical goal. Trials employing combinations of direct-acting antivirals that include NS5A inhibitors have shown significant promise in...
4.
Henderson J, Bilimoria D, Bubenik M, Cadilhac C, Cottrell K, Denis F, et al.
Bioorg Med Chem Lett
. 2015 Jan;
25(4):948-51.
PMID: 25577039
Inhibitors of the HCV NS5A nonstructural protein are showing promising clinical potential in the treatment of hepatitis C when used in combination with other direct-acting antiviral agents. Current NS5A clinical...
5.
Ahmad N, Gabius H, Andre S, Kaltner H, Sabesan S, Roy R, et al.
J Biol Chem
. 2003 Dec;
279(12):10841-7.
PMID: 14672941
Galectin-3 is unique among the galectin family of animal lectins in its biological activities and structure. Most members of the galectin family including galectin-1 possess apoptotic activities, whereas galectin-3 possesses...
6.
Andre S, Liu B, Gabius H, Roy R
Org Biomol Chem
. 2003 Dec;
1(22):3909-16.
PMID: 14664382
The interplay of mammalian lectins such as galectins with cellular glycoconjugates is intimately involved in crucial reaction pathways including tumor cell adhesion, migration or growth regulation. These clinically relevant functions...
7.
8.
Dominique R, Das S, Liu B, Nahra J, Schmor B, Gan Z, et al.
Methods Enzymol
. 2003 Sep;
362:17-28.
PMID: 12968353
No abstract available.
9.
Liu B, Das S, Roy R
Org Lett
. 2002 Aug;
4(16):2723-6.
PMID: 12153219
[reaction: see text] Cross-metatheses of allyl halides and terminal olefins mediated by catalyst 2 are reported and showed good yield and excellent E/Z selectivity. The application of these compounds as...
10.
Liu B, Roy R
Chem Commun (Camb)
. 2002 Jul;
(6):594-5.
PMID: 12120139
A hexameric disaccharide cluster bearing the terminal Gal alpha related xenotransplantation antigen was constructed using a sequence of ruthenium carbenoid catalyzed olefin self-metathesis of monoallylated tribenzyl pentaerythritol followed, after interconversion...