Biji Mathew
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Explore the profile of Biji Mathew including associated specialties, affiliations and a list of published articles.
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30
Citations
1008
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Recent Articles
1.
Amankwa C, Acha L, Dibas A, Chavala S, Roth S, Mathew B, et al.
Cells
. 2024 Mar;
13(5.
PMID: 38474360
Methods: To induce I/R injury and inflammation, we subjected R28 and primary microglial cells to oxygen glucose deprivation (OGD) for 6 h in vitro or treated these cells with a...
2.
Epshtein Y, Mathew B, Chen W, Jacobson J
Cells
. 2023 Oct;
12(19).
PMID: 37830619
GADD45a is a gene we previously reported as a mediator of responses to acute lung injury. GADD45a-/- mice express decreased Akt and increased Akt ubiquitination due to the reduced expression...
3.
Mathew B, Acha L, Torres L, Huang C, Liu A, Kalinin S, et al.
Acta Biomater
. 2023 Jan;
158:782-797.
PMID: 36638942
Mesenchymal stem cell (MSCs)-derived extracellular vesicles (EVs) are emerging therapeutic tools. Hypoxic pre-conditioning (HPC) of MSCs altered the production of microRNAs (miRNAs) in EVs, and enhanced the cytoprotective, anti-inflammatory, and...
4.
Aneesh A, Liu A, Moss H, Feinstein D, Ravindran S, Mathew B, et al.
Stem Cell Res Ther
. 2021 Dec;
12(1):594.
PMID: 34863294
Background: Optic neuritis (ON) is frequently encountered in multiple sclerosis, neuromyelitis optica spectrum disorder, anti-myelin oligodendrocyte glycoprotein associated disease, and other systemic autoimmune disorders. The hallmarks are an abnormal optic...
5.
Mathew B, Torres L, Acha L, Tran S, Liu A, Patel R, et al.
Cells
. 2021 Apr;
10(4).
PMID: 33806128
Cell replacement therapy using mesenchymal (MSC) and other stem cells has been evaluated for diabetic retinopathy and glaucoma. This approach has significant limitations, including few cells integrated, aberrant growth, and...
6.
Mathew B, Chennakesavalu M, Sharma M, Torres L, Stelman C, Tran S, et al.
Autophagy
. 2020 May;
17(6):1479-1499.
PMID: 32452260
Retinal ischemia is a major cause of vision loss and a common underlying mechanism associated with diseases, such as diabetic retinopathy and central retinal artery occlusion. We have previously demonstrated...
7.
Mathew B, Ravindran S, Liu X, Torres L, Chennakesavalu M, Huang C, et al.
Biomaterials
. 2019 Jan;
197:146-160.
PMID: 30654160
Retinal ischemia is a major cause of vision loss and impairment and a common underlying mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central retinal artery occlusion. The...
8.
Lederer P, Zhou T, Chen W, Epshtein Y, Wang H, Mathew B, et al.
Vascul Pharmacol
. 2018 Jul;
110:16-23.
PMID: 29969688
Acute lung injury (ALI) is characterized by endothelial barrier disruption resulting in increased vascular permeability. As focal adhesion kinase (FAK), a non-receptor protein tyrosine kinase, is involved in endothelial cell...
9.
Kadzielawa K, Mathew B, Stelman C, Lei A, Torres L, Roth S
Graefes Arch Clin Exp Ophthalmol
. 2018 Mar;
256(5):935-949.
PMID: 29504043
Purpose: The pathophysiology of retinal ischemia involves mechanisms including inflammation and apoptosis. Ischemic post-conditioning (Post-C), a brief non-lethal ischemia, induces a long-term ischemic tolerance, but the mechanisms of ischemic post-conditioning...
10.
Sun X, Mathew B, Sammani S, Jacobson J, Garcia J
Pulm Circ
. 2017 Jul;
7(1):117-125.
PMID: 28680571
We have demonstrated that simvastatin and sphingosine 1-phosphate (S1P) both attenuate increased vascular permeability in preclinical models of acute respiratory distress syndrome. However, the underlying mechanisms remain unclear. As Krüppel-like...